Sisák Anita, Polanek Evelin, Molnár Regina, Szabó Andrea, Rárosi Ferenc, Hosseini Armita, Németh Gábor, Orvos Hajnalka, Paulik Edit
Department of Public Health, Albert Szent-Györgyi Medical School, University of Szeged, 6720 Szeged, Hungary.
Doctoral School of Experimental and Preventive Medicine, University of Szeged, 6720 Szeged, Hungary.
J Pers Med. 2025 Jul 3;15(7):287. doi: 10.3390/jpm15070287.
Perinatal depression is one of the most common mental illnesses in women. The aim of this study was to assess the association of life stressors, perceived stress, obstetric and neonatal complications, and depressive symptoms in the early postpartum period and to compare these variables in two groups of women (preterm and term deliveries). : A case-control study was conducted among 300 women who gave birth in 2019 at the University of Szeged. Cases included women with preterm deliveries (<37 weeks, n = 100), and the controls included women with term deliveries (≥37 weeks, n = 200). Data were collected during postpartum hospital stays through a self-administered questionnaire (containing validated questionnaires: the Holmes-Rahe Life Stress Inventory, the Perceived Stress Scale (PSS-14), and the Edinburgh Postnatal Depression Scale (EPDS)) and the medical records of women and newborns. A descriptive statistical analysis and logistic regression were used to identify predictors of high EPDS scores (≥10). : Perceived stress levels were significantly higher among cases than controls ( < 0.001). Higher perceived stress was associated with a higher risk of depression in cases (OR: 1.31, 95% CI: 1.17-1.48, < 0.001) and controls (OR: 1.33, 95% CI: 1.21-1.45, < 0.001), too. Newborn complications were associated with an increased perinatal depression risk in the controls (OR: 2.48, 95% CI: 1.05-5.91; = 0.039) but not in the cases (OR: 2.79, 95% CI: 0.79-9.85; = 0.111). It is supposed that premature birth was stressful itself, and women with preterm babies were less sensitive to any complications occurring in their newborns compared to women with term newborns. Neither maternal age, education, nor obstetric complications predicted depressive symptoms. : Our findings highlight the impact of maternal perceived stress and newborns' health status on the risk of developing depression during the early postpartum period. These results emphasize the need for ongoing screening and follow-up measures, especially for women with higher EPDS scores.
围产期抑郁症是女性中最常见的精神疾病之一。本研究的目的是评估产后早期生活压力源、感知压力、产科和新生儿并发症与抑郁症状之间的关联，并比较两组女性（早产和足月分娩）的这些变量。：对2019年在塞格德大学分娩的300名女性进行了一项病例对照研究。病例包括早产（<37周，n = 100）的女性，对照组包括足月分娩（≥37周，n = 200）的女性。在产后住院期间，通过一份自我管理问卷（包含经过验证的问卷：霍尔姆斯-拉赫生活压力量表、感知压力量表（PSS - 14）和爱丁堡产后抑郁量表（EPDS））以及女性和新生儿的病历收集数据。采用描述性统计分析和逻辑回归来确定EPDS评分高（≥10）的预测因素。：病例组的感知压力水平显著高于对照组（<0.001）。在病例组（OR：1.31，95%CI：1.17 - 1.48，<0.001）和对照组（OR：1.33，95%CI：1.21 - 1.45，<0.001）中，较高的感知压力也与更高的抑郁风险相关。新生儿并发症与对照组围产期抑郁症风险增加相关（OR：2.48，95%CI：1.05 - 5.91；=0.039），但在病例组中不相关（OR：2.79，95%CI：0.79 - 9.85；=0.111）。据推测，早产本身就具有压力，与足月新生儿的女性相比，早产女婴的母亲对新生儿出现的任何并发症不太敏感。母亲年龄、教育程度和产科并发症均不能预测抑郁症状。：我们的研究结果突出了母亲感知压力和新生儿健康状况对产后早期患抑郁症风险的影响。这些结果强调了持续筛查和随访措施的必要性，特别是对于EPDS评分较高的女性。
