Mazza Marianna, Avallone Carla, Kotzalidis Georgios Demetrios, Marano Giuseppe, Moccia Lorenzo, Serio Anna Maria, Balocchi Marta, Sessa Ilenia, Janiri Delfina, De Luca Ilaria, Brisi Caterina, Spera Maria Chiara, Monti Laura, Gonsalez Del Castillo Angela, Angeletti Gloria, Chieffo Daniela, Rinaldi Lucio, Janiri Luigi, Lanzone Antonio, Scambia Giovanni, Mercuri Eugenio Maria, Sani Gabriele
Institute of Psychiatry and Psychology, Department of Geriatrics, Neuroscience and Orthopedics, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
NESMOS Department (Neurosciences, Mental Health, and Sensory Organs), Faculty of Medicine and Psychology, Sapienza University of Rome, 00189 Rome, Italy.
J Pers Med. 2023 Jan 25;13(2):211. doi: 10.3390/jpm13020211.
Pregnancy is a unique experience in women's life, requiring a great ability of adaptation and self-reorganization; vulnerable women may be at increased risk of developing depressive symptoms. This study aimed to examine the incidence of depressive symptomatology during pregnancy and to evaluate the role of affective temperament traits and psychosocial risk factors in predicting them. We recruited 193 pregnant women, collected data regarding sociodemographic, family and personal clinical variables, social support and stressful life events and administered the Mood Disorder Questionnaire (MDQ), the Patient Health Questionnaire-9 (PHQ-9), and the Temperament Evaluation of Memphis, Pisa, Paris and San Diego-Autoquestionnaire (TEMPS-A). In our sample, prevalence of depressive symptomatology was 41.45% and prevalence of depression was 9.85% (6.75% mild and 3.10% moderate depression). We have chosen a cutoff >4 on PHQ-9 to identify mild depressive symptoms which may predict subsequent depression. Statistically significant differences between the two groups were found in the following factors: gestational age, occupation, partner, medical conditions, psychiatric disorders, family psychiatric history, stressful life events, and TEMPS-A mean scores. In our sample mean scores on all affective temperaments but the hyperthymic, were significantly lower in the control group. Only depressive and hyperthymic temperaments were found to be, respectively, risk and protective factors for depressive symptomatology. The current study confirms the high prevalence and complex aetiology of depressive symptomatology during pregnancy and suggests that affective temperament assessment seems to be a useful adjunctive instrument to predict depressive symptomatology during pregnancy and postpartum.
怀孕是女性生命中的一段独特经历,需要很强的适应能力和自我调整能力;脆弱的女性出现抑郁症状的风险可能会增加。本研究旨在调查孕期抑郁症状的发生率,并评估情感气质特质和心理社会风险因素在预测这些症状方面的作用。我们招募了193名孕妇,收集了有关社会人口统计学、家庭和个人临床变量、社会支持和应激性生活事件的数据,并进行了心境障碍问卷(MDQ)、患者健康问卷-9(PHQ-9)以及孟菲斯、比萨、巴黎和圣地亚哥气质评估-自陈问卷(TEMPS-A)的测试。在我们的样本中,抑郁症状的患病率为41.45%,抑郁症的患病率为9.85%(轻度抑郁症为6.75%,中度抑郁症为3.10%)。我们选择PHQ-9得分>4作为识别可能预测后续抑郁症的轻度抑郁症状的临界值。在以下因素中发现两组之间存在统计学上的显著差异:孕周、职业、伴侣、医疗状况、精神障碍、家族精神病史、应激性生活事件以及TEMPS-A平均得分。在我们的样本中,除了环性心境气质外,所有情感气质的平均得分在对照组中均显著较低。仅发现抑郁气质和环性心境气质分别是抑郁症状的风险因素和保护因素。当前研究证实了孕期抑郁症状的高患病率和复杂病因,并表明情感气质评估似乎是预测孕期和产后抑郁症状的一种有用辅助工具。