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钙化冠状动脉病变的管理

Management of Calcified Coronary Lesions.

作者信息

Al-Shaibi Khaled, Bharadwaj Aditya, Mathur Atul, Jaikishen Ashish, Riley Robert

机构信息

Cardiac Center, King Fahd Armed Forces Hospital Jeddah, Saudi Arabia.

Division of Cardiology, Loma Linda University Medical Center Loma Linda, CA.

出版信息

US Cardiol. 2024 Jan 24;18:e01. doi: 10.15420/usc.2022.29. eCollection 2024.

DOI:10.15420/usc.2022.29
PMID:39494408
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11526476/
Abstract

With an aging population, coronary calcification is increasingly encountered in modern day interventional practice. Unfortunately, it is associated with lower procedural success and higher rates of periprocedural complications, such as failure to deliver stents, perforations, dissections, and other major adverse cardiac events. Furthermore, suboptimal stent deployment in the setting of severe calcification is associated with both short-and long-term major adverse cardiac events, including stent thrombosis, MI, in-stent restenosis, and target lesion revascularization. A variety of treatment options for these lesions exist, including specialized balloons, atherectomy, and intravascular lithotripsy. While there is currently no universally accepted algorithm for choosing between these treatment strategies, several different algorithms exist, and the optimization of these treatment regimens will continue to evolve in the coming years. This review aims to provide insights on the different therapeutic modalities and an understanding of the current body of evidence.

摘要

随着人口老龄化,冠状动脉钙化在现代介入治疗实践中越来越常见。不幸的是,它与较低的手术成功率和较高的围手术期并发症发生率相关,如支架输送失败、穿孔、夹层以及其他主要不良心脏事件。此外,在严重钙化情况下支架植入不理想与短期和长期主要不良心脏事件相关,包括支架血栓形成、心肌梗死、支架内再狭窄和靶病变血运重建。针对这些病变有多种治疗选择,包括专用球囊、旋切术和血管内碎石术。虽然目前在这些治疗策略之间尚无普遍接受的算法,但存在几种不同的算法,并且这些治疗方案的优化在未来几年将持续发展。本综述旨在提供关于不同治疗方式的见解以及对当前证据的理解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e82/11526476/b465acd84d8c/usc-18-e01-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e82/11526476/6d624eaa0126/usc-18-e01-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e82/11526476/e4f88caf12a2/usc-18-e01-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e82/11526476/56ec4afa8cce/usc-18-e01-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e82/11526476/b465acd84d8c/usc-18-e01-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e82/11526476/6d624eaa0126/usc-18-e01-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e82/11526476/e4f88caf12a2/usc-18-e01-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e82/11526476/56ec4afa8cce/usc-18-e01-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e82/11526476/b465acd84d8c/usc-18-e01-g004.jpg

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J Pers Med. 2022 Oct 3;12(10):1638. doi: 10.3390/jpm12101638.
2
Intravascular lithotripsy during percutaneous coronary intervention: current concepts.经皮冠状动脉介入治疗中的血管内碎石术:当前概念。
Expert Rev Cardiovasc Ther. 2022 Apr;20(4):323-338. doi: 10.1080/14779072.2022.2069561. Epub 2022 Apr 25.
3
Intravascular Ultrasound-Derived Calcium Score to Predict Stent Expansion in Severely Calcified Lesions.血管内超声衍生的钙评分预测严重钙化病变中的支架扩张。
Circ Cardiovasc Interv. 2021 Oct;14(10):e010296. doi: 10.1161/CIRCINTERVENTIONS.120.010296. Epub 2021 Oct 19.
4
Principles of Intravascular Lithotripsy for Calcific Plaque Modification.血管内碎石术治疗钙化斑块修饰的原则。
JACC Cardiovasc Interv. 2021 Jun 28;14(12):1275-1292. doi: 10.1016/j.jcin.2021.03.036.
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Intravascular Lithotripsy for Treatment of Calcified Coronary Lesions: Patient-Level Pooled Analysis of the Disrupt CAD Studies.血管内碎石术治疗钙化性冠状动脉病变:Disrupt CAD 研究的患者水平汇总分析。
JACC Cardiovasc Interv. 2021 Jun 28;14(12):1337-1348. doi: 10.1016/j.jcin.2021.04.015. Epub 2021 May 3.
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When to use intravascular ultrasound or optical coherence tomography during percutaneous coronary intervention?在经皮冠状动脉介入治疗期间何时使用血管内超声或光学相干断层扫描?
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