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钙化冠状动脉病变的管理

Management of Calcified Coronary Lesions.

作者信息

Al-Shaibi Khaled, Bharadwaj Aditya, Mathur Atul, Jaikishen Ashish, Riley Robert

机构信息

Cardiac Center, King Fahd Armed Forces Hospital Jeddah, Saudi Arabia.

Division of Cardiology, Loma Linda University Medical Center Loma Linda, CA.

出版信息

US Cardiol. 2024 Jan 24;18:e01. doi: 10.15420/usc.2022.29. eCollection 2024.

Abstract

With an aging population, coronary calcification is increasingly encountered in modern day interventional practice. Unfortunately, it is associated with lower procedural success and higher rates of periprocedural complications, such as failure to deliver stents, perforations, dissections, and other major adverse cardiac events. Furthermore, suboptimal stent deployment in the setting of severe calcification is associated with both short-and long-term major adverse cardiac events, including stent thrombosis, MI, in-stent restenosis, and target lesion revascularization. A variety of treatment options for these lesions exist, including specialized balloons, atherectomy, and intravascular lithotripsy. While there is currently no universally accepted algorithm for choosing between these treatment strategies, several different algorithms exist, and the optimization of these treatment regimens will continue to evolve in the coming years. This review aims to provide insights on the different therapeutic modalities and an understanding of the current body of evidence.

摘要

随着人口老龄化,冠状动脉钙化在现代介入治疗实践中越来越常见。不幸的是,它与较低的手术成功率和较高的围手术期并发症发生率相关,如支架输送失败、穿孔、夹层以及其他主要不良心脏事件。此外,在严重钙化情况下支架植入不理想与短期和长期主要不良心脏事件相关,包括支架血栓形成、心肌梗死、支架内再狭窄和靶病变血运重建。针对这些病变有多种治疗选择,包括专用球囊、旋切术和血管内碎石术。虽然目前在这些治疗策略之间尚无普遍接受的算法,但存在几种不同的算法,并且这些治疗方案的优化在未来几年将持续发展。本综述旨在提供关于不同治疗方式的见解以及对当前证据的理解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e82/11526476/6d624eaa0126/usc-18-e01-g001.jpg

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