Department of Urology, Ogaki Municipal Hospital, Ogaki 5038502, Japan.
Department of Urology, Gifu University Graduate School of Medicine, Gifu 5011194, Japan.
Medicina (Kaunas). 2022 Oct 19;58(10):1488. doi: 10.3390/medicina58101488.
: We aimed to investigate the rate of incidence and risk factors of post-transplant urinary tract infection (UTI) in patients receiving kidney transplantation (KT) at our institution. : A retrospective cohort study was carried out on patients who underwent KT for end-stage kidney disease (ESKD) from January 2008 to December 2021 at Gifu University Hospital. UTI was defined as the existence of bacterial and/or fungal infection in urine with ≥105 colony-forming units/mL, with or without urinary and/or systemic symptoms of UTI. Patients were divided into two groups: those with UTI after KT (UTI group) and those without UTI (non-UTI group). The primary endpoint of this study was the relationship between covariates and UTI after KT. : Two hundred and forty patients with ESKD received KT at Gifu University Hospital. Thirty-four participants developed UTI after surgery, and the most common pathogen was . At the end of the follow-up, graft loss was observed in six patients (2.5%), independent of UTI episodes. In the multivariate analysis, diabetes mellitus (DM) was statistically associated with post-transplant UTI in kidney transplant recipients. : Preoperative serum glucose control in patients with DM may have a crucial role in preventing UTI and preserving renal function after KT.
我们旨在调查本机构肾移植(KT)患者术后尿路感染(UTI)的发生率和风险因素。
对 2008 年 1 月至 2021 年 12 月在岐阜大学医院接受终末期肾病(ESKD)KT 的患者进行了回顾性队列研究。UTI 的定义为尿液中存在细菌和/或真菌感染,≥105 个菌落形成单位/毫升,伴有或不伴有 UTI 的尿路和/或全身症状。患者分为两组:KT 后发生 UTI(UTI 组)和未发生 UTI(非 UTI 组)。本研究的主要终点是协变量与 KT 后 UTI 的关系。
240 名 ESKD 患者在岐阜大学医院接受 KT。34 名参与者术后发生 UTI,最常见的病原体是 。在随访结束时,6 名患者(2.5%)发生移植物丢失,与 UTI 发作无关。多变量分析显示,糖尿病(DM)与肾移植受者术后 UTI 有统计学关联。
DM 患者术前血清血糖控制可能对预防 UTI 和保护 KT 后肾功能至关重要。