市售产品对四氢大麻酚毛发浓度的影响。
Manipulation of THC Hair Concentrations by Commercially Available Products.
作者信息
Bertges Markus, Ketikidou Alexandra, Weiskirchen Ralf, van Helden Josef, Boehnke Rudolf, Hess Cornelius
机构信息
MVZ Dr. Stein + Kollegen Mönchengladbach, Labor Mönchengladbach, Medical Care Centre, D-41169 Mönchengladbach, Germany.
Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry (IFMPEGKC), RWTH University Hospital Aachen, D-52074 Aachen, Germany.
出版信息
Metabolites. 2022 Sep 24;12(10):900. doi: 10.3390/metabo12100900.
Many drug tests are carried out by means of hair analysis. The aim of the present study was to clarify if and to what extent it is possible to manipulate the results of hair analyses on tetrahydrocannabinol (THC) by using various commercially available everyday products and products advertised on the internet to be able to reduce the concentrations of drugs in hair. Fifty-four THC-positive hair samples were analyzed using liquid chromatography tandem mass spectrometry; they were analyzed untreated or treated with Vodka Gorbatschow (n = 19), Seborin hair tonic (n = 11), Zydot shampoo (n = 6), Desderman disinfectant (n = 11) and Head and Shoulders shampoo (n = 7). A mean reduction of 52% (Zydot shampoo) to 65% (Desderman) was shown. Hair treatments could not be detected visually. Hair concentrations could also be decreased to non-detectability by using these everyday hair care products. Therefore, it is recommended to complement abstinence controls using hair samples by urine analysis and to not over-interpret quantitative results of THC concentrations in hair.
许多药物检测是通过毛发分析进行的。本研究的目的是明确是否以及在何种程度上可以通过使用各种市售日常用品和互联网上宣传的产品来操纵四氢大麻酚（THC）毛发分析结果，从而降低毛发中的药物浓度。使用液相色谱串联质谱法对54份THC阳性毛发样本进行分析；对其进行未经处理或用哥萨克伏特加（n = 19）、丝宝护发素（n = 11）、Zydot洗发水（n = 6）、德施曼消毒剂（n = 11）和海飞丝洗发水（n = 7）处理后的分析。结果显示，THC浓度平均降低了52%（Zydot洗发水）至65%（德施曼消毒剂）。肉眼无法检测到毛发处理情况。使用这些日常护发产品也可将毛发中的THC浓度降低至无法检测的水平。因此，建议通过尿液分析来补充使用毛发样本进行的禁欲检测，并且不要过度解读毛发中THC浓度的定量结果。
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