基于细胞膜调控改善冻干存活率。（原句表述不太完整准确，推测大概意思如此翻译）

Improvement of Freeze-Dried Survival of Based on Cell Membrane Regulation.

作者信息

Cui Shumao, Hu Kai, Qian Zhihao, Mao Bingyong, Zhang Qiuxiang, Zhao Jianxin, Tang Xin, Zhang Hao

机构信息

State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.

School of Food Science and Technology, Jiangnan University, Wuxi 214122, China.

出版信息

Microorganisms. 2022 Oct 7;10(10):1985. doi: 10.3390/microorganisms10101985.

The cell membrane of is a key structure for cell survival. In this study, we aimed to improve the lyophilization resistance of by regulating the cell membrane structure. Unsaturated fatty acids or cell membrane-regulating substances were added during culturing to determine their effect on the composition of cell membrane fatty acids and the survival rate of the cells after freeze-drying. The results showed that Tween 80, β-carotene and melatonin increased the lyophilization survival rate of by 9.44, 14.53, and 18.34%, respectively. After adding a lyophilization protective agent at a concentration of 21.49% at a 1:1 ratio, a combination of Tween 80, melatonin, and β-carotene was added to regulate the cell membrane, which increased the lyophilization survival rate by 32.08-86.05%. This study proposes new research directions and ideas for improving the survival rate of probiotics for industrial production.

（此处原文缺失具体的细胞名称）的细胞膜是细胞存活的关键结构。在本研究中，我们旨在通过调节细胞膜结构来提高（此处原文缺失具体的细胞名称）的冻干抗性。在培养过程中添加不饱和脂肪酸或细胞膜调节物质，以确定它们对细胞膜脂肪酸组成和冻干后细胞存活率的影响。结果表明，吐温80、β-胡萝卜素和褪黑素分别使（此处原文缺失具体的细胞名称）的冻干存活率提高了9.44%、14.53%和18.34%。以1:1的比例添加浓度为21.49%的冻干保护剂后，添加吐温80、褪黑素和β-胡萝卜素的组合来调节细胞膜，使冻干存活率提高了32.08 - 86.05%。本研究为提高工业生产中益生菌的存活率提出了新的研究方向和思路。