超声辅助制备辛烯基琥珀酸酐大米淀粉的姜黄素乳液载体的应用。
Application of Curcumin Emulsion Carrier from Ultrasonic-Assisted Prepared Octenyl Succinic Anhydride Rice Starch.
机构信息
Ningxia Key Laboratory for Food Microbial Applications Technology and Safety Control, Ningxia University, Yinchuan 750021, China.
College of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang Key Laboratory for Agro-Food Processing, Integrated Research Base of Southern Fruit and Vegetable Preservation Technology, Zhejiang International Scientific and Technological Cooperation Base of Health Food Manufacturing and Quality Control, Zhejiang University, Hangzhou 310058, China.
出版信息
Molecules. 2022 Oct 17;27(20):6955. doi: 10.3390/molecules27206955.
The emulsification of ultrasonic-assisted prepared octenyl succinic anhydride (OSA) rice starch on curcumin was investigated in the present study. The results indicated that the encapsulation efficiency of curcumin in emulsions stabilized by OSA-ultrasonic treatment rice starch was improved, from 81.65 ± 0.14% to 89.03 ± 0.09%. During the in vitro oral digestion, the particle size and Zeta potential of the curcumin emulsion did not change significantly (p > 0.05). During the in vitro digestive stage of the stomach and small intestine, the particle size of the curcumin emulsion continued to increase, and the absolute potential continued to decrease. Our work showed that OSA-pre-treatment ultrasonic rice starch could improve curcumin bioavailability by increasing the encapsulation efficiency with stronger stability to avoid the attack of enzymes and high intensity ion, providing a way to develop new emulsion-based delivery systems for bioactive lipophilic compounds using OSA starch.
本研究考察了超声辅助制备的辛烯基琥珀酸酐（OSA）大米淀粉对姜黄素的乳化作用。结果表明，OSA-超声处理大米淀粉稳定的乳液中姜黄素的包埋效率从 81.65±0.14%提高到 89.03±0.09%。在体外口服消化过程中，姜黄素乳液的粒径和 Zeta 电位没有显著变化（p＞0.05）。在胃和小肠的体外消化阶段，姜黄素乳液的粒径持续增加，绝对电势持续下降。我们的工作表明，OSA 预处理超声大米淀粉可以通过提高包埋效率来提高姜黄素的生物利用度，同时具有更强的稳定性以避免酶和高强度离子的攻击，为开发基于 OSA 淀粉的新型脂溶性生物活性化合物乳液输送系统提供了一种方法。
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