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妊娠期间饮食模式与妊娠期高血压的关系:“生于沈阳”队列研究。

Associations of Dietary Patterns during Pregnancy with Gestational Hypertension: The "Born in Shenyang" Cohort Study.

机构信息

Health Sciences Institute, China Medical University, Shenyang 110122, China.

Research Center of China Medical University Birth Cohort, China Medical University, Shenyang 110122, China.

出版信息

Nutrients. 2022 Oct 17;14(20):4342. doi: 10.3390/nu14204342.

Abstract

The literature on maternal dietary patterns and gestational hypertension (GH) risk is largely ambiguous. We investigated the associations of maternal dietary patterns with GH risk among 1092 pregnant women in a Chinese pre-birth cohort. We used both three-day food diaries (TFD) and food frequency questionnaires (FFQ) to assess the diets of pregnant women. Principal components analysis with varimax rotation was used to identify dietary patterns from the TFD and FFQ, respectively. In total, 14.5% of the participants were diagnosed with GH. Maternal adherence to a “Wheaten food−coarse cereals pattern (TFD)” was associated with a lower risk of GH (quartile 3 [Q3] vs. Q1, odds ratio [OR] = 0.53, 95%CI: 0.31, 0.90). Maternal adherence to a “Sweet food−seafood pattern (TFD)” was associated with lower systolic blood pressure (Q4 vs. Q1, β = −2.57, 95%CI: −4.19, −0.96), and mean arterial pressure (Q4 vs. Q1, β = −1.54, 95%CI: −2.70, −0.38). The protective associations of the “Sweet food-seafood (TFD)” and “Fish−seafood pattern (FFQ)” with the risk of GH were more pronounced among women who were overweight/obese before pregnancy (p for interaction < 0.05 for all). The findings may help to develop interventions and better identify target populations for hypertension prevention during pregnancy.

摘要

关于孕妇饮食模式与妊娠期高血压(GH)风险的文献结果并不明确。我们在中国的一项产前队列研究中,调查了孕妇饮食模式与 GH 风险之间的关系。我们使用了三天食物日记(TFD)和食物频率问卷(FFQ)来评估孕妇的饮食。分别采用主成分分析和方差极大旋转法从 TFD 和 FFQ 中提取饮食模式。共有 1092 名孕妇参与了研究,其中 14.5%被诊断为 GH。孕妇坚持“麦类食物-粗粮模式(TFD)”与 GH 风险降低相关(Q3 与 Q1 相比,比值比 [OR] = 0.53,95%置信区间 [CI]:0.31,0.90)。孕妇坚持“甜食-海鲜模式(TFD)”与收缩压降低相关(Q4 与 Q1 相比,β = -2.57,95%CI:-4.19,-0.96),与平均动脉压降低相关(Q4 与 Q1 相比,β = -1.54,95%CI:-2.70,-0.38)。“甜食-海鲜(TFD)”和“鱼类-海鲜模式(FFQ)”与 GH 风险之间的保护关联在妊娠前超重/肥胖的女性中更为明显(所有交互作用的 P 值均<0.05)。这些发现可能有助于制定干预措施,并更好地确定妊娠期间高血压预防的目标人群。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/182a/9611399/decab937120b/nutrients-14-04342-g001.jpg

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