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采用协同凝集试验对细菌性脑膜炎进行快速实验室诊断。

Rapid laboratory diagnosis of bacterial meningitis employing coagglutination test.

作者信息

Samad Talukder M A, Corker A, Greensides R A

出版信息

Trop Geogr Med. 1987 Apr;39(2):133-6.

PMID:3629705
Abstract

Twenty samples of CSF, 11 from proven meningitis with positive culture and nine negative controls were examined. Ten cases (91%) of meningitis, six caused by Haemophilus influenzae, three by Streptococcus pneumoniae and one by Neisseria meningitidis have been diagnosed by the coagglutination method. Using the Phadebact CSF kit, the test was negative, in one (9%) meningitis case, which was caused by Str. pneumoniae. Subsequently all cases of meningitis were confirmed by isolation of the organisms in CSF culture. None of the nine control CSF gave a positive reaction with coagglutination test or positive culture. The coagglutination test is simple, rapid and requires no special equipment.

摘要

对20份脑脊液样本进行了检测,其中11份来自培养阳性的确诊脑膜炎患者,9份为阴性对照。通过协同凝集试验诊断出10例(91%)脑膜炎患者,其中6例由流感嗜血杆菌引起,3例由肺炎链球菌引起,1例由脑膜炎奈瑟菌引起。使用Phadebact脑脊液检测试剂盒时,1例(9%)由肺炎链球菌引起的脑膜炎病例检测结果为阴性。随后,所有脑膜炎病例均通过脑脊液培养分离出病原体得到确诊。9份对照脑脊液样本中,无一例协同凝集试验呈阳性反应或培养结果阳性。协同凝集试验简单、快速,且无需特殊设备。

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