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[对鸡胚具有胚胎毒性和致畸作用的有机溶剂研究]

[Organic solvents studied for their embryotoxic and teratogenic action on chick embryos].

作者信息

Chakŭrov R, Iotsev M

出版信息

Vet Med Nauki. 1987;24(5):60-3.

PMID:3629964
Abstract

Tested were the embryotoxic and teratogenic effects of some organic solvents (dioxane, propylene glycol, ethylene glycol, ethyl alcohol, and tween-80). The solvents were introduced into 3-day-old chick embryos at the rate of 0.1 cm3 in the yolk sac. With the exception of the 5th group (20 per cent ethylene glycol) in all other test groups mortality rate reached 100 per cent, manifested up to the 14th day. No teratogenic effects with expressed malformations were observed.

摘要

测试了某些有机溶剂(二氧六环、丙二醇、乙二醇、乙醇和吐温80)的胚胎毒性和致畸性。将这些溶剂以0.1立方厘米的量注入3日龄鸡胚的卵黄囊中。除第5组(20%乙二醇)外,所有其他测试组的死亡率在第14天前达到100%。未观察到有明显畸形的致畸作用。

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