Chen Kai, Zhao Rui
Department of Otorhinolaryngology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Otorhinolaryngology-Head and Neck Surgery, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Ear Nose Throat J. 2025 Aug;104(8):NP476-NP489. doi: 10.1177/01455613221137122. Epub 2022 Oct 27.
ObjectiveTo systematically review the results of type 1 tympanoplasties with temporalis fascia (TF) vs cartilage grafts in patients with chronic otitis media.MethodsEligible studies were identified from PubMed, Ovid, and EMBASE databases prior to November 2021. We analyzed the pure tone audiometry (PTA) and air-bone gap (ABG) data as continuous variables, and the success rate was analyzed as a dichotomous variable.ResultsForty-four studies, including 4582 patients, were eligible. The cartilage graft overall morphologic success rate was higher than that of the TF grafts ( < .001). In the palisade ( < .004) and island grafts ( < .001) subgroups, the analysis was significantly different. However, there was no significant difference in the inlay butterfly grafts subgroup. For hearing outcomes, the analysis revealed that TF grafts had a smaller mean post-operative ABG ( = .009). However, the subgroup analysis showed no significant difference in the mean post-operative ABG. For PTA, there was no significant difference in hearing improvement. However, the palisade cartilage graft subgroup resulted in a better hearing outcome than the TF graft subgroup in terms of the mean post-operative PTA ( = .007). There was no significant difference in the functional success rate or mean ABG gain.ConclusionCartilage grafts have a better success rate than TF grafts in tympanoplasty. Both cartilage and TF tympanoplasty provided similar improvements in hearing outcome, while TF grafts generated a better outcome in post-operative ABG and palisade cartilage grafts in post-operative PTA. This may be related to the biological characteristics of the grafts. Further thorough studies need to be conducted.
目的
系统评价慢性中耳炎患者采用颞肌筋膜(TF)与软骨移植行Ⅰ型鼓室成形术的结果。
方法
在2021年11月之前从PubMed、Ovid和EMBASE数据库中检索符合条件的研究。我们将纯音听力测定(PTA)和气骨导间距(ABG)数据作为连续变量进行分析,将成功率作为二分变量进行分析。
结果
44项研究符合条件,包括4582例患者。软骨移植的总体形态学成功率高于TF移植(P<0.001)。在栅栏状(P<0.004)和岛状移植(P<0.001)亚组中,分析有显著差异。然而,镶嵌式蝶形移植亚组中无显著差异。对于听力结果,分析显示TF移植术后平均ABG较小(P=0.009)。然而,亚组分析显示术后平均ABG无显著差异。对于PTA,听力改善无显著差异。然而,就术后平均PTA而言,栅栏状软骨移植亚组的听力结果优于TF移植亚组(P=0.007)。功能成功率或平均ABG增益无显著差异。
结论
在鼓室成形术中,软骨移植的成功率高于TF移植。软骨和TF鼓室成形术在听力结果方面提供了相似的改善,而TF移植在术后ABG方面产生了更好的结果,并在术后PTA方面栅栏状软骨移植产生了更好的结果。这可能与移植材料的生物学特性有关。需要进一步进行深入研究。