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软骨鼓膜成形术是否比筋膜鼓膜成形术更有效?一项系统评价。

Is cartilage tympanoplasty more effective than fascia tympanoplasty? A systematic review.

机构信息

Department of Otolaryngology, Ninewells Hospital and Medical School, Dundee, UK.

出版信息

Otol Neurotol. 2012 Jul;33(5):699-705. doi: 10.1097/MAO.0b013e318254fbc2.

Abstract

OBJECTIVE

A systematic review to compare the effectiveness of the use of cartilage (with or without perichondrium) with temporalis fascia used in tympanoplasty.

DATA SOURCE

The following databases were searched for relevant studies: MEDLINE, Embase, CINAHL, the Cochrane Library including the Cochrane Central Register of Controlled Trials, Google scholar, and the PubMed. There was no restriction as to the design or date of publication.

STUDY SELECTIONS

We selected randomized controlled trials (RCTs) and retrospective studies comparing cartilage and temporalis fascia tympanoplasty in relation to 2 outcomes: morphological and functional success. Initial search identified 2,091 publications. All titles and abstracts were reviewed by 2 of the authors, and 103 relevant articles were studied. However, only 14 studies met the inclusion criteria for this review. These included 3 RCTs, 10 retrospective studies, and 1 literature review.

RESULTS

Three level 1 (RCTs) and 11 level 3 and 4 evidence-based studies were included (n = 1,475 patients). One RCT and 3 retrospective studies showed a statistically significant better morphological success, that is, intact ear drum with cartilage graft with or without perichondrium. There was, however, no statistically significant difference between cartilage and temporalis fascia tympanoplasty regarding function, namely, hearing outcome. The need for revision rates was approximately 10% with cartilage and 19% with fascia tympanoplasty.

CONCLUSION

Tympanoplasty using cartilage with or without perichondrium has better morphological outcome than tympanoplasty using temporalis fascia. However, there was no statistically significant difference in hearing outcomes between the 2 grafts.

摘要

目的

系统评价比较使用软骨(带或不带软骨膜)与颞筋膜在鼓室成形术中的效果。

资料来源

检索了以下数据库中的相关研究:MEDLINE、Embase、CINAHL、Cochrane 图书馆(包括 Cochrane 对照试验中心注册库)、Google Scholar 和 PubMed。设计或出版日期没有限制。

研究选择

我们选择了随机对照试验(RCT)和回顾性研究,比较了软骨和颞筋膜在以下两种结果方面的鼓室成形术:形态和功能成功。最初的搜索确定了 2091 篇出版物。所有标题和摘要均由 2 位作者进行了审查,并研究了 103 篇相关文章。然而,只有 14 项研究符合本综述的纳入标准。其中包括 3 项 RCT、10 项回顾性研究和 1 项文献综述。

结果

纳入了 3 项 1 级(RCT)和 11 项 3 级和 4 级证据的研究(n=1475 例患者)。1 项 RCT 和 3 项回顾性研究显示,形态学成功的统计学意义更大,即使用软骨移植物(带或不带软骨膜)的完整鼓膜。然而,在功能(即听力结果)方面,软骨和颞筋膜鼓室成形术之间没有统计学上的显著差异。软骨和筋膜鼓室成形术的修复率约为 10%和 19%。

结论

使用软骨(带或不带软骨膜)的鼓室成形术比使用颞筋膜的鼓室成形术具有更好的形态学结果。然而,两种移植物在听力结果方面没有统计学上的显著差异。

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