Institute for Chemical Research, Kyoto University, Uji, Kyoto 611-0011, Japan.
Digital Lab Division, Fujitsu Limited, Saiwai-ku, Kawasaki, Kanagawa 212-0014, Japan.
Nucleic Acids Res. 2023 Jan 6;51(D1):D587-D592. doi: 10.1093/nar/gkac963.
KEGG (https://www.kegg.jp) is a manually curated database resource integrating various biological objects categorized into systems, genomic, chemical and health information. Each object (database entry) is identified by the KEGG identifier (kid), which generally takes the form of a prefix followed by a five-digit number, and can be retrieved by appending /entry/kid in the URL. The KEGG pathway map viewer, the Brite hierarchy viewer and the newly released KEGG genome browser can be launched by appending /pathway/kid, /brite/kid and /genome/kid, respectively, in the URL. Together with an improved annotation procedure for KO (KEGG Orthology) assignment, an increasing number of eukaryotic genomes have been included in KEGG for better representation of organisms in the taxonomic tree. Multiple taxonomy files are generated for classification of KEGG organisms and viruses, and the Brite hierarchy viewer is used for taxonomy mapping, a variant of Brite mapping in the new KEGG Mapper suite. The taxonomy mapping enables analysis of, for example, how functional links of genes in the pathway and physical links of genes on the chromosome are conserved among organism groups.
KEGG（https://www.kegg.jp）是一个人工整理的数据库资源，整合了各种生物对象，分为系统、基因组、化学和健康信息。每个对象（数据库条目）都由 KEGG 标识符（kid）标识，通常采用前缀加五位数字的形式，可以通过在 URL 中附加 /entry/kid 来检索。KEGG 途径图查看器、Brite 层次结构查看器和新发布的 KEGG 基因组浏览器可以通过在 URL 中分别附加 /pathway/kid、/brite/kid 和 /genome/kid 来启动。随着 KO（KEGG 直系同源物）分配注释过程的改进，越来越多的真核生物基因组被纳入 KEGG，以更好地表示分类树中的生物。为了对 KEGG 生物和病毒进行分类，生成了多个分类法文件，并使用 Brite 层次结构查看器进行分类法映射，这是新的 KEGG Mapper 套件中 Brite 映射的变体。分类法映射可以分析例如，途径中基因的功能链接和染色体上基因的物理链接在生物群之间是如何保守的。
