School of Dentistry, The University of Queensland, Brisbane, Queensland, Australia.
Department of Neurology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
J Oral Rehabil. 2023 Jan;50(1):62-68. doi: 10.1111/joor.13387. Epub 2022 Nov 7.
Multiple sclerosis (MS) is a leading cause of neurological disability in young and middle-aged populations, associated with substantial burden of illness. Because a growing literature now shows that this burden extends to poorer oral health, oral health-related quality of life (OHRQoL) may be reduced as well.
To test whether people with relapsing-remitting MS (RRMS) have poorer OHRQoL than demographically matched controls, and to establish which variables are associated with worse OHRQoL.
In total, 64 people with RRMS and 69 demographically matched controls participated. Both groups completed the Oral Health Impact Profile (OHIP-14), a validated measure of OHRQoL, as well as an objective oral health examination performed by a qualified dentist, a measure of dental-related functionality and a measure of mental health.
OHRQoL was significantly poorer in the RRMS relative to the control group. However, although poorer OHRQoL in the RRMS group was moderately associated with objectively assessed oral health (r = .30), it was more strongly associated with mental health (r = .61). For the control group, the reverse pattern of association was evident, with OHRQoL more strongly associated with oral health (r = .48) relative to mental health (r = .20).
People with RRMS report poorer OHRQoL than demographically matched controls, but these appraisals are more strongly linked to mental health than to objective oral health indicators.
多发性硬化症（MS）是导致年轻和中年人群神经功能障碍的主要原因，与疾病负担有很大关系。由于越来越多的文献表明这种负担延伸到较差的口腔健康，口腔健康相关生活质量（OHRQoL）也可能会降低。
测试复发缓解型多发性硬化症（RRMS）患者的 OHRQoL 是否比人口统计学匹配的对照组差，并确定哪些变量与较差的 OHRQoL 相关。
共有 64 名 RRMS 患者和 69 名人口统计学匹配的对照组参加了研究。两组均完成了口腔健康影响量表（OHIP-14），这是一种经过验证的 OHRQoL 测量工具，以及由合格牙医进行的客观口腔健康检查、口腔功能测量和心理健康测量。
RRMS 组的 OHRQoL 明显比对照组差。然而，尽管 RRMS 组的 OHRQoL 与客观评估的口腔健康中度相关（r=0.30），但与心理健康的相关性更强（r=0.61）。对于对照组，情况正好相反，OHRQoL 与口腔健康的相关性更强（r=0.48），而与心理健康的相关性较弱（r=0.20）。
RRMS 患者报告的 OHRQoL 比人口统计学匹配的对照组差，但这些评估与心理健康的相关性强于与客观口腔健康指标的相关性。
