Tc-标记干细胞在慢性肾脏病评估中的应用。
The Use of Tc-Labeled Stem Cells for Evaluation of Chronic Kidney Disease.
机构信息
Department of Radiology, School of Medicine, Laboratório de Marcação de Células e Moléculas (LMCM), Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
出版信息
Methods Mol Biol. 2023;2575:297-304. doi: 10.1007/978-1-0716-2716-7_15.
PMID:36301482
Abstract
The labeling of stem cells with radionuclides allows in vivo monitoring of cell migration and homing. Here, we describe the labeling of mononuclear stem cells with 99mTc and show their biodistribution in preclinical models and patients with chronic kidney disease.
摘要
放射性核素标记干细胞可实现细胞迁移和归巢的体内监测。本研究描述了单核干细胞的 99mTc 标记，并展示了其在临床前模型和慢性肾脏病患者中的体内分布。
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