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先天性宫颈闭锁的重建手术:系统评价。

Reconstructive surgery for congenital atresia of the uterine cervix: a systematic review.

机构信息

Department of Obstetrics and Gynecology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Via Commenda 12, 20122, Milan, Italy.

Obstetrics and Gynecology Division B, Azienda Ospedaliera Integrata, University of Verona, Verona, Italy.

出版信息

Arch Gynecol Obstet. 2023 Sep;308(3):685-700. doi: 10.1007/s00404-022-06825-5. Epub 2022 Oct 28.

Abstract

The authors discuss the incidence, the embryological development, the classification, the presentation and the treatment options of this rare reproductive tract abnormality. In the past, the treatment proposed almost unanimously was hysterectomy and subsequent construction, when necessary, of a neovagina. In recent decades, numerous experiences of conservative therapies have accumulated that allow the restoration of menstrual function and in some rare cases even the achievement of a pregnancy. However, complications associated with recanalization of the cervix frequently resulted in the need for repeated surgery, risk of serious and sometimes fatal ascending infection. This review aims to analyze the most recent and significant experiences of conservative surgery in this field to provide an accurate picture of the various techniques and their outcomes, especially from the point of view of fertility. Conservative surgery should now be considered as the first-line treatment option. On the other hand, it is not possible to draw conclusions on the superiority of one technique over another among the various conservative options. This would require large series with adequate follow-up, which unfortunately are not available.

摘要

作者讨论了这种罕见的生殖道畸形的发生率、胚胎发育、分类、表现和治疗选择。过去,几乎一致提出的治疗方法是子宫切除术和随后的阴道重建,必要时还可以建立新的阴道。近几十年来,已经积累了许多保守治疗的经验,这些经验可以恢复月经功能,在某些罕见情况下甚至可以实现妊娠。然而,与宫颈再通相关的并发症经常导致需要反复手术,并且存在严重且有时致命的上行感染的风险。本综述旨在分析该领域最近和最重要的保守手术经验,以准确了解各种技术及其结果,特别是从生育的角度来看。保守手术现在应该被视为一线治疗选择。另一方面,对于各种保守选择中哪种技术具有优势,我们无法得出结论。这需要有足够随访的大型系列,但遗憾的是,目前尚无此类研究。

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