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腹腔镜辅助下对一名非典型宫颈阴道畸形患者进行子宫阴道吻合术:病例报告

Laparoscopy-assisted uterovaginal anastomosis in a patient with atypical cervicovaginal malformation: a case report.

作者信息

Naem Antoine, Moufawad Graziella, Sultan Suzana, Sleiman Zaki

机构信息

Faculty of Mathematics and Computer Science, University of Bremen, Bremen, Germany.

Lebanese American University Medical Center -Rizk Hospital, Beirut, Lebanon.

出版信息

Front Med (Lausanne). 2025 Jul 9;12:1604463. doi: 10.3389/fmed.2025.1604463. eCollection 2025.

DOI:10.3389/fmed.2025.1604463
PMID:40703289
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12283993/
Abstract

Cervicovaginal anomalies are rare and form 4-7% of the Müllerian anomalies. Traditionally, cervicovaginal agenesis/dysgenesis had been treated by hysterectomy due to the high risks of restenosis and sepsis which are associated with cervical canalization. In this work, we report the case of a 14-year-old patient who presented with amenorrhea and cyclic abdominal pain. The patient had normal secondary sexual development. Magnetic resonance imaging revealed hematometra and bilateral hematosalpinx. Laparoscopic exploration identified an obstructed cervix and blunt vagina. The patient underwent direct cervicovaginal anastomosis under laparoscopic guidance. After 1 month of follow-up, the patient had normal menstruation and a healthy uterine cavity and cervical canal upon hysteroscopy.

摘要

宫颈阴道畸形较为罕见,占苗勒管畸形的4 - 7%。传统上,由于宫颈管形成术存在再狭窄和败血症的高风险,宫颈阴道发育不全/发育异常一直通过子宫切除术进行治疗。在本研究中,我们报告了一名14岁出现闭经和周期性腹痛的患者病例。该患者第二性征发育正常。磁共振成像显示子宫积血和双侧输卵管积血。腹腔镜探查发现宫颈梗阻和阴道钝性狭窄。患者在腹腔镜引导下接受了直接宫颈阴道吻合术。随访1个月后,患者月经正常,宫腔镜检查显示子宫腔和宫颈管健康。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2a5/12283993/e9933212ce4a/fmed-12-1604463-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2a5/12283993/59407b140166/fmed-12-1604463-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2a5/12283993/1b558ece16b9/fmed-12-1604463-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2a5/12283993/e9933212ce4a/fmed-12-1604463-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2a5/12283993/59407b140166/fmed-12-1604463-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2a5/12283993/1b558ece16b9/fmed-12-1604463-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2a5/12283993/e9933212ce4a/fmed-12-1604463-g003.jpg

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本文引用的文献

1
An Investigation of Depressive Symptoms in Patients with Congenital Cervical and Vaginal Aplasia: A Cross-Sectional Study.先天性宫颈和阴道发育不全患者抑郁症状的调查:一项横断面研究。
Int J Womens Health. 2022 Nov 17;14:1621-1627. doi: 10.2147/IJWH.S384339. eCollection 2022.
2
Reconstructive surgery for congenital atresia of the uterine cervix: a systematic review.先天性宫颈闭锁的重建手术:系统评价。
Arch Gynecol Obstet. 2023 Sep;308(3):685-700. doi: 10.1007/s00404-022-06825-5. Epub 2022 Oct 28.
3
Functional and Reproductive Outcomes Following Surgical Management of Congenital Anomalies of the Cervix: A Systematic Review.
先天性宫颈畸形手术治疗后的功能及生殖结局:一项系统评价
J Minim Invasive Gynecol. 2021 Aug;28(8):1452-1461.e16. doi: 10.1016/j.jmig.2020.10.030. Epub 2021 May 29.
4
Reproductive surgery for müllerian anomalies: a review of progress in the last decade.苗勒氏管畸形的生殖外科治疗:近十年进展回顾。
Fertil Steril. 2019 Sep;112(3):408-416. doi: 10.1016/j.fertnstert.2019.07.005.
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The ESHRE/ESGE consensus on the classification of female genital tract congenital anomalies.ESHRE/ESGE 关于女性生殖道先天性畸形分类的共识。
Hum Reprod. 2013 Aug;28(8):2032-44. doi: 10.1093/humrep/det098. Epub 2013 Jun 14.
6
Laparoscopic-assisted uterovaginal anastomosis for uterine cervix atresia with vaginal aplasia using a silicone stent lined with acellular porcine small intestinal submucosa graft inserted using a 16F Foley catheter.腹腔镜辅助硅胶支架联合脱细胞猪小肠黏膜下层补片行 16F Foley 尿管置入在先天性宫颈闭锁伴阴道缺如中的应用
J Minim Invasive Gynecol. 2013 Sep-Oct;20(5):710-3. doi: 10.1016/j.jmig.2013.03.010. Epub 2013 May 14.
7
Congenital anomalies of the uterine cervix: lessons from 30 cases managed clinically by a common protocol.先天性宫颈畸形:30 例临床管理中采用通用方案的经验教训。
Fertil Steril. 2010 Oct;94(5):1858-63. doi: 10.1016/j.fertnstert.2009.10.024. Epub 2009 Nov 25.
8
Surgical correction of congenital atresia of the cervix.
Am J Obstet Gynecol. 1958 Sep;76(3):643-6. doi: 10.1016/0002-9378(58)90084-x.
9
Utero-vaginal anastomosis in women with uterine cervix atresia: long-term follow-up and reproductive performance. A study of 18 cases.子宫颈闭锁女性的子宫-阴道吻合术:长期随访与生殖性能。18例研究。
Hum Reprod. 2001 Aug;16(8):1722-5. doi: 10.1093/humrep/16.8.1722.
10
Clinical implications of uterine malformations and hysteroscopic treatment results.子宫畸形的临床意义及宫腔镜治疗结果
Hum Reprod Update. 2001 Mar-Apr;7(2):161-74. doi: 10.1093/humupd/7.2.161.