Ethicon Inc., NJ, USA.
OPEN Health, Bethesda, MD, USA.
J Comp Eff Res. 2022 Dec;11(17):1231-1240. doi: 10.2217/cer-2021-0218. Epub 2022 Oct 28.
Bleeding during spine surgery is controlled using topical hemostatic agents. Studies have reported outcomes between Surgiflo and Floseal, the most widely used flowable hemostatic matrices, but have not included the latest Surgiflo formulation which is more adherent to the bleeding surface than prior formulations. A propensity score-matched analysis was conducted using the Premier Healthcare Database to compare economic and clinical outcomes of adults undergoing inpatient spinal surgery between 2013 and 2018 receiving current Surgiflo or Floseal. This retrospective study included 28,910 patients in each group and found comparable outcomes for bleeding events, overall transfusion rate, inpatient mortality and readmissions between Surgiflo and Floseal. Surgiflo was associated with $430 (USD) lower hospitalization costs, shorter length of stay and shorter operating room time than Floseal.
在脊柱手术中，使用局部止血剂来控制出血。有研究报告了 Surgiflo 和 Floseal 之间的结果，这两种是最广泛使用的可流动止血基质，但没有包括最新的 Surgiflo 配方，它比以前的配方更能粘附在出血表面。利用 Premier Healthcare Database 进行了倾向评分匹配分析，以比较 2013 年至 2018 年期间接受当前 Surgiflo 或 Floseal 的住院脊柱手术成年人的经济和临床结果。这项回顾性研究包括每组 28910 名患者，发现 Surgiflo 和 Floseal 之间的出血事件、总输血率、住院死亡率和再入院率结果相当。与 Floseal 相比，Surgiflo 的住院费用降低了 430 美元（USD），住院时间和手术室时间更短。
