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Reduced FVIII recovery associated with anti-FVIII PEG antibodies after BNT162b2 SARS-CoV-2 vaccination.

作者信息

Valsecchi Carla, Gualtierotti Roberta, Arcudi Sara, Ciavarella Alessandro, Schiavone Lucia, Novembrino Cristina, Siboni Simona Maria, Mannucci Pier Mannuccio, Peyvandi Flora

机构信息

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy.

Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milan, Italy.

出版信息

Blood Adv. 2023 Jan 10;7(1):174-177. doi: 10.1182/bloodadvances.2022008989.

DOI:10.1182/bloodadvances.2022008989
PMID:36306338
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9635221/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bc8/9811197/4478b6f4f201/BLOODA_ADV-2022-008989-gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bc8/9811197/288f687a5752/BLOODA_ADV-2022-008989-fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bc8/9811197/09ddd06fbf10/BLOODA_ADV-2022-008989-gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bc8/9811197/4478b6f4f201/BLOODA_ADV-2022-008989-gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bc8/9811197/288f687a5752/BLOODA_ADV-2022-008989-fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bc8/9811197/09ddd06fbf10/BLOODA_ADV-2022-008989-gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bc8/9811197/4478b6f4f201/BLOODA_ADV-2022-008989-gr2.jpg

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Blood Adv. 2023 Feb 28;7(4):620-629. doi: 10.1182/bloodadvances.2022007529.
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Anti-PEG Antibodies Boosted in Humans by SARS-CoV-2 Lipid Nanoparticle mRNA Vaccine.SARS-CoV-2脂质纳米颗粒mRNA疫苗可增强人体中的抗聚乙二醇抗体。
ACS Nano. 2022 Aug 23;16(8):11769-11780. doi: 10.1021/acsnano.2c04543. Epub 2022 Jun 27.
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Impact of anti-PEG antibody affinity on accelerated blood clearance of pegylated epoetin beta in mice.
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Mol Ther Methods Clin Dev. 2023 May 11;29:450-459. doi: 10.1016/j.omtm.2023.05.008. eCollection 2023 Jun 8.
抗聚乙二醇抗体亲和力对聚乙二醇化促红细胞生成素β在小鼠体内加速血液清除的影响。
Biomed Pharmacother. 2022 Feb;146:112502. doi: 10.1016/j.biopha.2021.112502. Epub 2021 Dec 7.
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