Laihinen A, Alihanka J, Raitasuo S, Rinne U K
Acta Neurol Scand. 1987 Jul;76(1):64-8. doi: 10.1111/j.1600-0404.1987.tb03546.x.
Nine parkinsonian patients were studied during one night using the static charge sensitive bed (SCSB) method for the monitoring of respiration, ballistocardiogram (BCG) and body movements. The parkinsonian sleep was more restless than that of the controls. As the SCSB-defined levels of autonomic nervous activity were concerned, the amount of motor active wakefulness (MAW) was significantly (P less than 0.05) increased in parkinsonian patients, who also had less quiet sleep (P less than 0.05) than the controls. Parkinsonian tremor was present during 29.8 +/- 15.8% of the time in bed. Usually it was observed during wakefulness; it disappeared when the patient fell asleep. The frequency of turning-over events in bed was smaller in the parkinsonian patients than in the controls (P less than 0.05). When the heart rate changes associated with sleep movements were studied it was found that the parasympathetic deceleration component in the parkinsonian patients was absent. The motor dysfunction associated with Parkinson's disease is reflected in many ways in the sleep movement activity. Sleep disturbances in PD seem to be secondary in character; i.e. they can be due to impaired motor functions like turning around in the bed, or due to impaired arousal mechanisms during sleep.
对9名帕金森病患者进行了为期一晚的研究，采用静电荷敏感床（SCSB）方法监测呼吸、心冲击图（BCG）和身体运动。帕金森病患者的睡眠比对照组更不安宁。就SCSB定义的自主神经活动水平而言，帕金森病患者的运动活跃觉醒（MAW）量显著增加（P<0.05），且安静睡眠比对照组少（P<0.05）。帕金森病震颤出现在床上时间的29.8±15.8%。通常在觉醒时观察到；患者入睡时消失。帕金森病患者在床上翻身事件的频率低于对照组（P<0.05）。研究与睡眠运动相关的心率变化时发现，帕金森病患者缺乏副交感神经减速成分。帕金森病相关的运动功能障碍在睡眠运动活动中有多种表现。帕金森病中的睡眠障碍似乎是继发性的；即，它们可能是由于在床上翻身等运动功能受损，或由于睡眠期间觉醒机制受损所致。
