Larsen N P, Forwood M R, Parker A W
Acta Orthop Scand. 1987 Jun;58(3):260-4. doi: 10.3109/17453678709146480.
Fifty male rats, aged 40 days, were assigned to one of five groups to examine the influence of immobilization and retraining on the strength and elastic stiffness of the anterior and posterior cruciate ligaments. Following the experimental treatments, the anterior ligament from the right leg and the posterior ligament from the left leg were tested in tension at a separation speed of 50 mm/min. After 4 weeks of cast immobilization, the separation force of the anterior ligament declined by one fourth and elastic stiffness of both ligaments declined by one fourth and one third, respectively. No changes occurred in the separation force of the posterior ligament. Following a 6-week retraining swimming program, the separation force and elastic stiffness values had returned to control levels. Additionally, there was a transition from avulsion type failures in the immobilized groups of animals to insertion site and intraligament failures in animals subjected to rehabilitative swimming exercise. This was indicative of a return in the strength of the osseous component of the bone-ligament-bone complex following immobilization.
50只40日龄的雄性大鼠被分为五组，以研究固定和再训练对前后交叉韧带强度和弹性刚度的影响。经过实验处理后，以50毫米/分钟的分离速度对右腿的前交叉韧带和左腿的后交叉韧带进行拉伸测试。在石膏固定4周后，前交叉韧带的分离力下降了四分之一，两条韧带的弹性刚度分别下降了四分之一和三分之一。后交叉韧带的分离力没有变化。经过为期6周的再训练游泳计划后，分离力和弹性刚度值已恢复到对照水平。此外，在固定组动物中，失败类型从撕脱型转变为接受康复性游泳锻炼动物的插入部位和韧带内失败型。这表明固定后骨-韧带-骨复合体骨成分的强度有所恢复。
