Oral and Maxillofacial Surgery Department, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.
School of medicine, Iran university of medical sciences, Tehran, Iran.
Cancer Rep (Hoboken). 2023 Jan;6(1):e1751. doi: 10.1002/cnr2.1751. Epub 2022 Oct 28.
Peripheral T-Cell Lymphoma Not Otherwise Specified (PTCL-NOS) is a rare type of non-Hodgkin T-cell lymphoma which frequently seen in immunocompromised individuals. It is estimated that only 2% of lymphomas are located on the buccal mucosa. In this case report, we present a 34-year-old male with a PTCL diagnosis.
A 34-year-old immune-competent male presented with a buccal progressive ulcerated lesion. Histopathologic and immunohistochemical findings were compatible with PTCL-NOS and classified as stage IIEA according to the Ann Arbor staging. The patient underwent chemotherapy followed by radiotherapy. He remained disease-free after 12 months of follow-up.
Although lymphoma is uncommon in the oral cavity, physicians especially dentists in ordinary dental checkups should consider persistent progressive lesions as an important differential diagnosis of lymphoma.
未特指的外周 T 细胞淋巴瘤（PTCL-NOS）是一种罕见的非霍奇金 T 细胞淋巴瘤，常见于免疫功能低下的个体。据估计，只有 2%的淋巴瘤位于颊黏膜。在本病例报告中，我们介绍了一位 34 岁的男性，他患有 PTCL。
一位 34 岁免疫功能正常的男性出现颊部进行性溃疡性病变。组织病理学和免疫组织化学检查结果与 PTCL-NOS 相符，并根据安阿伯分期系统分类为 IIEA 期。患者接受了化疗，随后进行了放疗。在 12 个月的随访中，他无疾病复发。
尽管淋巴瘤在口腔中不常见，但医生，特别是普通牙科检查中的牙医，应将持续进行性病变视为淋巴瘤的一个重要鉴别诊断。
