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口腔周围 T 细胞淋巴瘤:一例报告。

Peripheral T-cell lymphoma of the oral cavity: A case report.

机构信息

Oral and Maxillofacial Surgery Department, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.

School of medicine, Iran university of medical sciences, Tehran, Iran.

出版信息

Cancer Rep (Hoboken). 2023 Jan;6(1):e1751. doi: 10.1002/cnr2.1751. Epub 2022 Oct 28.

Abstract

BACKGROUND

Peripheral T-Cell Lymphoma Not Otherwise Specified (PTCL-NOS) is a rare type of non-Hodgkin T-cell lymphoma which frequently seen in immunocompromised individuals. It is estimated that only 2% of lymphomas are located on the buccal mucosa. In this case report, we present a 34-year-old male with a PTCL diagnosis.

CASE

A 34-year-old immune-competent male presented with a buccal progressive ulcerated lesion. Histopathologic and immunohistochemical findings were compatible with PTCL-NOS and classified as stage IIEA according to the Ann Arbor staging. The patient underwent chemotherapy followed by radiotherapy. He remained disease-free after 12 months of follow-up.

CONCLUSION

Although lymphoma is uncommon in the oral cavity, physicians especially dentists in ordinary dental checkups should consider persistent progressive lesions as an important differential diagnosis of lymphoma.

摘要

背景

未特指的外周 T 细胞淋巴瘤(PTCL-NOS)是一种罕见的非霍奇金 T 细胞淋巴瘤,常见于免疫功能低下的个体。据估计,只有 2%的淋巴瘤位于颊黏膜。在本病例报告中,我们介绍了一位 34 岁的男性,他患有 PTCL。

病例

一位 34 岁免疫功能正常的男性出现颊部进行性溃疡性病变。组织病理学和免疫组织化学检查结果与 PTCL-NOS 相符,并根据安阿伯分期系统分类为 IIEA 期。患者接受了化疗,随后进行了放疗。在 12 个月的随访中,他无疾病复发。

结论

尽管淋巴瘤在口腔中不常见,但医生,特别是普通牙科检查中的牙医,应将持续进行性病变视为淋巴瘤的一个重要鉴别诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3381/9875683/80fc7127ddf3/CNR2-6-e1751-g001.jpg

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