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在贫困劳动者中使用生物制剂治疗银屑病的公平性。

Equity in the usage of biologics for psoriasis in the working poor.

作者信息

Eley Sarah J, DeMeo Dustin P, Korman Neil J, Carroll Bryan T

机构信息

College of Medicine, Northeast Ohio Medical University, Rootstown, OH, USA.

School of Medicine, Case Western Reserve University, Cleveland, OH, USA.

出版信息

Arch Dermatol Res. 2023 May;315(4):1029-1031. doi: 10.1007/s00403-022-02410-7. Epub 2022 Oct 28.

Abstract

Biologic therapy often produces excellent outcomes for psoriasis; however, their high cost may create a barrier to appropriate usage, especially in the working poor population. This study defines working poor as income below 150% of the federal poverty level and holding or seeking work at least half a year. Our study aims to identify gaps in access to biologic therapy for psoriasis based on working poor status. This retrospective cross-sectional study was conducted utilizing data from the Medical Expenditure Panel Survey (MEPS) from 2007 to 2018. Patients were stratified into working poor (57,091), non-working poor (43,421), and non-poor (693,841) groups for analysis. In univariate analysis, WP (4.0%, ph p = 0.003) and NWP (2.8%, ph p = 0.006) were less likely to use biologics than NP (15.8%) (X p < 0.001). A binary logistic regression showed that WP vs. NP status (OR 0.27, p = 0.05), female vs. male sex (OR 0.55, p = 0.05), Black vs. White race (OR 0.14, p = 0.02), and Medicare vs. private insurance (OR 0.09, p = 0.03) had lower odds of using biologics. After correcting for age, sex, race, and insurance, WP confers an independent risk factor to lower biologic prescriptions. The high cost of biologics in the setting of financial barriers for some patients should be considered by physicians prescribing biologic therapy for psoriasis.

摘要

生物疗法通常能为银屑病带来出色的治疗效果;然而,其高昂的成本可能会成为合理使用的障碍,尤其是在低收入在职人群中。本研究将低收入在职人群定义为收入低于联邦贫困线150%且持有工作或求职至少半年的人群。我们的研究旨在确定基于低收入在职状态的银屑病生物疗法获取方面的差距。这项回顾性横断面研究利用了2007年至2018年医疗支出面板调查(MEPS)的数据。患者被分为低收入在职组(57,091人)、非低收入在职组(43,421人)和非贫困组(693,841人)进行分析。在单因素分析中,低收入在职组(4.0%,ph p = 0.003)和非低收入在职组(2.8%,ph p = 0.006)使用生物制剂的可能性低于非贫困组(15.8%)(X p < 0.001)。二元逻辑回归显示,低收入在职组与非贫困组状态(OR 0.27,p = 0.05)、女性与男性性别(OR 0.55,p = 0.05)、黑人与白人种族(OR 0.14,p = 0.02)以及医疗保险与私人保险(OR 0.09,p = 0.03)使用生物制剂的几率较低。在校正年龄、性别、种族和保险因素后,低收入在职状态是生物制剂处方减少的独立危险因素。对于为银屑病患者开具生物疗法处方的医生来说,应考虑到某些患者在经济障碍情况下生物制剂的高成本问题。

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