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胶囊内镜中小肠清洁度:使用验证的人工智能算法的病例对照研究。

Small bowel cleanliness in capsule endoscopy: a case-control study using validated artificial intelligence algorithm.

机构信息

Department of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, 27 Dongguk-Ro, Ilsandong-Gu, Goyang, 10326, Republic of Korea.

Department of Electronics Engineering, Chungbuk National University, Cheongju, Republic of Korea.

出版信息

Sci Rep. 2022 Oct 29;12(1):18265. doi: 10.1038/s41598-022-23181-1.

DOI:10.1038/s41598-022-23181-1
PMID:36309541
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9617876/
Abstract

Small bowel capsule endoscopy (SBCE) may need to be performed immediately after colonoscopy without additional bowel preparation if active small bowel diseases are suspected. However, it is unclear whether the small bowel cleanliness is adequately maintained even after SBCE is performed immediately after colonoscopy. We compared the small bowel cleanliness scores of the study group (SBCE immediately after colonoscopy) and control group (SBCE alone) using a validated artificial intelligence (AI) algorithm (cut-off score > 3.25 for adequate). Cases of SBCE in which polyethylene glycol was used were included retrospectively. Among 85 enrolled cases, 50 cases (58.8%) were the study group. The mean time from the last dose of purgative administration to SBCE was 6.86 ± 0.94 h in the study group and 3.00 ± 0.18 h in the control group. Seventy-five cases (88.2%) were adequate small bowel cleanliness, which was not different between the two groups. The mean small bowel cleanliness score for the study group was 3.970 ± 0.603, and for the control group was 3.937 ± 0.428. In the study group, better colon preparation resulted in a higher small bowel cleanliness score (p = 0.015). Small bowel cleanliness was also adequately maintained in SBCE immediately after colonoscopy. There was no difference between the time and volume of purgative administration and small bowel cleanliness.

摘要

小肠胶囊内镜 (SBCE) 可能需要在疑似活动性小肠疾病的情况下,在结肠镜检查后立即进行,而无需额外的肠道准备。然而,尚不清楚在结肠镜检查后立即进行 SBCE 是否能充分保持小肠清洁。我们使用经过验证的人工智能 (AI) 算法(适当的分界值>3.25)比较了研究组(结肠镜检查后立即进行 SBCE)和对照组(单独进行 SBCE)的小肠清洁度评分。回顾性纳入使用聚乙二醇进行 SBCE 的病例。在 85 例纳入的病例中,50 例(58.8%)为研究组。研究组从最后一次泻药给药到 SBCE 的平均时间为 6.86±0.94 小时,对照组为 3.00±0.18 小时。75 例(88.2%)的小肠清洁度适当,两组之间无差异。研究组的平均小肠清洁度评分为 3.970±0.603,对照组为 3.937±0.428。在研究组中,更好的结肠准备导致更高的小肠清洁度评分(p=0.015)。在结肠镜检查后立即进行 SBCE 也能充分保持小肠清洁。泻药的时间和剂量与小肠清洁度之间无差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86a9/9617876/3e5a34be23fd/41598_2022_23181_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86a9/9617876/11408edfef82/41598_2022_23181_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86a9/9617876/87024b0ccf48/41598_2022_23181_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86a9/9617876/b64cf90c2b74/41598_2022_23181_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86a9/9617876/563770824c99/41598_2022_23181_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86a9/9617876/3e5a34be23fd/41598_2022_23181_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86a9/9617876/11408edfef82/41598_2022_23181_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86a9/9617876/87024b0ccf48/41598_2022_23181_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86a9/9617876/b64cf90c2b74/41598_2022_23181_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86a9/9617876/563770824c99/41598_2022_23181_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86a9/9617876/3e5a34be23fd/41598_2022_23181_Fig5_HTML.jpg

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本文引用的文献

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Diagnostics (Basel). 2022 Apr 28;12(5):1105. doi: 10.3390/diagnostics12051105.
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Development and Verification of a Deep Learning Algorithm to Evaluate Small-Bowel Preparation Quality.用于评估小肠准备质量的深度学习算法的开发与验证
Diagnostics (Basel). 2021 Jun 20;11(6):1127. doi: 10.3390/diagnostics11061127.
3
Preparation, Timing, Prokinetics, and Surface Agents in Video Capsule Endoscopy.
视频胶囊内镜中的准备、时机、促动力剂和表面活性剂。
Gastrointest Endosc Clin N Am. 2021 Apr;31(2):251-265. doi: 10.1016/j.giec.2020.12.012. Epub 2021 Feb 15.
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Prospective evaluation of third-generation small bowel capsule endoscopy videos by independent readers demonstrates poor reproducibility of cleanliness classifications.前瞻性评估第三代小肠胶囊内镜视频由独立读者表明清洁分类的重现性差。
Clin Res Hepatol Gastroenterol. 2021 Nov;45(6):101612. doi: 10.1016/j.clinre.2020.101612. Epub 2021 Mar 16.
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Development of a deep learning-based software for calculating cleansing score in small bowel capsule endoscopy.开发一种基于深度学习的软件,用于计算小肠胶囊内镜的清洁评分。
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