Bell J G, Keen C L, Lönnerdal B
Am J Dis Child. 1987 Oct;141(10):1128-32. doi: 10.1001/archpedi.1987.04460100106041.
Zinc and copper absorption from five infant cereal products mixed with water, human milk, or cow's milk was measured using an in vivo absorption model (rat pup) involving gastric intubation of extrinsically radiolabeled diets. Whole-body copper 64 uptake, nine hours after intubation, ranged from 14% to 31% of the dose given for the different cereal combinations. The resultant bioavailability of copper from human milk-cereal combinations (23% to 26%) was significantly lower than that from human milk alone (38%). Whole-body zinc 65 uptake, nine hours after intubation, ranged from 13% to 54% of the dose given for the different cereal combinations. These values were significantly lower than the whole-body zinc 65 uptake from milk alone (61%). Zinc availability was lower (13% to 25%) from dry cereal combinations that contained phytic acid (oatmeal and high-protein varieties) compared with the ready-to-serve cereal-fruit combinations (24% to 54%). The highest zinc uptake (37% to 54%) was from rice-fruit combinations that do not contain phytic acid. We estimated the amounts of zinc and copper that would be absorbed from these cereal products and speculated on the potential impact of these foods on the weaning infant's zinc and copper nutriture. Depending on the feeding practices employed during the weaning period, it is apparent that infant cereals may compromise utilization of zinc and copper from milk diets during weaning.
使用一种体内吸收模型（幼鼠）来测量五种婴儿谷物产品与水、母乳或牛奶混合后的锌和铜吸收情况，该模型涉及对经外部放射性标记的饮食进行胃插管。插管九小时后，全身对铜64的摄取量，因不同谷物组合而异，占所给剂量的14%至31%。母乳与谷物组合中铜的最终生物利用率（23%至26%）显著低于单纯母乳中的铜生物利用率（38%）。插管九小时后，全身对锌65的摄取量，因不同谷物组合而异，占所给剂量的13%至54%。这些数值显著低于单纯牛奶中全身对锌65的摄取量（61%）。与即食谷物 - 水果组合（24%至54%）相比，含有植酸的干谷物组合（燕麦片和高蛋白品种）中锌的利用率较低（13%至25%）。不含植酸的大米 - 水果组合中锌的摄取量最高（37%至54%）。我们估算了这些谷物产品中锌和铜的吸收量，并推测了这些食物对断奶婴儿锌和铜营养状况的潜在影响。根据断奶期间采用的喂养方式，很明显婴儿谷物可能会影响断奶期间婴儿从奶类饮食中对锌和铜的利用。
