纤维肌痛：流行病学与风险因素，叙利亚大马士革一项基于人群的病例对照研究
Fibromyalgia: epidemiology and risk factors, a population-based case-control study in Damascus, Syria.
作者信息
Alzabibi Mhd Amin, Shibani Mosa, Alsuliman Tamim, Ismail Hlma, Alasaad Suja, Torbey André, Altorkmani Abdallah, Sawaf Bisher, Ayoub Rita, Khalayli Naram, Kudsi Mayssoun
机构信息
Faculty of Medicine, Syrian Private University, Mazzeh Street, P.O. Box 36822, Damascus, Syrian Arab Republic.
Hematology and Cell Therapy Department, Saint-Antoine Hospital, AP-HP Sorbonne University, Paris, France.
出版信息
BMC Rheumatol. 2022 Oct 31;6(1):62. doi: 10.1186/s41927-022-00294-8.
BACKGROUND
Fibromyalgia is a chronic disease with a high burden. We aim to be the first to investigate the prevalence of fibromyalgia (FM) in Syria and assess its risk factors.
METHODS
A self-reported questionnaire was distributed to the public to identify fibromyalgia patients using the American College of Rheumatology (ACR) 2010 modified criteria. Identified cases were matched using age with controls free from rheumatic disorders that were randomly sampled from the same population.
RESULTS
Out of 2966 participants, 350 (11.8%) satisfied the diagnostic criteria. Of these, only 29 (8.2%) were previously diagnosed by a physician, 239 (68.3%) were females, and 69 (19.71%) were diagnosed with depression. Female sex (OR = 1.31), diagnosis of major depressive disorder (OR = 2.62), irritable bowel syndrome (OR = 1.8), and Restless legs syndrome (OR = 1.72) were associated with a higher likelihood of fibromyalgia.
CONCLUSION
Our study revealed one of the highest prevalence rates of fibromyalgia ever reported in the general population. Efforts must be intensified to increase awareness about this disease in Syrian society as well as among healthcare providers.
背景
纤维肌痛是一种负担沉重的慢性疾病。我们旨在率先调查叙利亚纤维肌痛（FM）的患病率并评估其危险因素。
方法
向公众发放一份自填式问卷，使用美国风湿病学会（ACR）2010年修订标准来识别纤维肌痛患者。将识别出的病例按年龄与从同一人群中随机抽取的无风湿性疾病的对照进行匹配。
结果
在2966名参与者中，350人（11.8%）符合诊断标准。其中，只有29人（8.2%）之前被医生诊断过，239人（68.3%）为女性，69人（19.71%）被诊断患有抑郁症。女性（比值比[OR]=1.31）、重度抑郁症诊断（OR=2.62）、肠易激综合征（OR=1.8）和不安腿综合征（OR=1.72）与纤维肌痛的较高可能性相关。
结论
我们的研究揭示了普通人群中报告的纤维肌痛患病率最高之一。必须加大力度，提高叙利亚社会以及医疗服务提供者对这种疾病的认识。
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