Kurland Jayde E, Coyle Walter J, Winkler Anne, Zable Elizabeth
Department of Gastroenterology, Naval Medical Center San Diego, San Diego, California, USA.
Dig Dis Sci. 2006 Mar;51(3):454-60. doi: 10.1007/s10620-006-3154-7.
The purpose of this study was to determine the point prevalence of depressive symptoms, using the PRIME-MD questionnaire, and irritable bowel syndrome (IBS), while comparing the Rome II to the Rome I criteria, in patients with fibromyalgia (FM) and rheumatologic controls in an outpatient setting. The prevalence of IBS in FM patients (n = 105) was 63% by Rome I and 81% by Rome II criteria. The prevalence of IBS in controls (n = 62) was 15% by Rome I and 24% by Rome II criteria (FM vs. control; P < 0.001). Depressive symptoms were met in 40% of FM patients and 8% of controls (P < 0.001). The coexistence of IBS and depressive symptoms in the FM patients was 31% (Rome I) and 34% (Rome II). The prevalence of IBS and depressive symptoms was higher in FM patients compared to the control population. Identification of IBS and depressive symptoms in FM patients might enable clinicians to better meet the needs of this patient population.
本研究旨在通过门诊环境，使用PRIME-MD问卷确定纤维肌痛（FM）患者及风湿性对照者中抑郁症状的时点患病率以及肠易激综合征（IBS），同时比较罗马II标准与罗马I标准。FM患者（n = 105）中IBS的患病率，按照罗马I标准为63%，按照罗马II标准为81%。对照者（n = 62）中IBS的患病率，按照罗马I标准为15%，按照罗马II标准为24%（FM与对照者比较；P < 0.001）。40%的FM患者存在抑郁症状，对照者中这一比例为8%（P < 0.001）。FM患者中IBS与抑郁症状并存的比例为31%（罗马I标准）和34%（罗马II标准）。与对照人群相比，FM患者中IBS和抑郁症状的患病率更高。识别FM患者中的IBS和抑郁症状可能使临床医生能够更好地满足这一患者群体的需求。
