Davis Brittany R, Garza AnnaCarolina, Church Jessica A
Department of Psychology, The University of Texas at Austin, Austin, TX, United States.
Front Neuroimaging. 2022;1. doi: 10.3389/fnimg.2022.981947. Epub 2022 Sep 12.
Cognitive neuroimaging researchers' ability to infer accurate statistical conclusions from neuroimaging depends greatly on the quality of the data analyzed. This need for quality control is never more evident than when conducting neuroimaging studies with children and adolescents. Developmental neuroimaging requires patience, flexibility, adaptability, extra time, and effort. It also provides us a unique, non-invasive way to understand the development of cognitive processes, individual differences, and the changing relations between brain and behavior over the lifespan. In this discussion, we focus on collecting magnetic resonance imaging (MRI) data, as it is one of the more complex protocols used with children and youth. Through our extensive experience collecting MRI datasets with children and families, as well as a review of current best practices, we will cover three main topics to help neuroimaging researchers collect high-quality datasets. First, we review key recruitment and retention techniques, and note the importance for consistency and inclusion across groups. Second, we discuss ways to reduce scan anxiety for families and ways to increase scan success by describing the pre-screening process, use of a scanner simulator, and the need to focus on participant and family comfort. Finally, we outline several important design considerations in developmental neuroimaging such as asking a developmentally appropriate question, minimizing data loss, and the applicability of public datasets. Altogether, we hope this article serves as a useful tool for those wishing to enter or learn more about developmental cognitive neuroscience.
认知神经影像学研究人员从神经影像中推断准确统计结论的能力在很大程度上取决于所分析数据的质量。这种对质量控制的需求在对儿童和青少年进行神经影像学研究时最为明显。发育神经影像学需要耐心、灵活性、适应性、额外的时间和精力。它还为我们提供了一种独特的、非侵入性的方式来理解认知过程的发展、个体差异以及大脑与行为在整个生命周期中不断变化的关系。在本次讨论中,我们将重点关注磁共振成像(MRI)数据的收集,因为它是用于儿童和青少年的较为复杂的方案之一。通过我们在收集儿童及其家庭的MRI数据集方面的丰富经验,以及对当前最佳实践的回顾,我们将涵盖三个主要主题,以帮助神经影像学研究人员收集高质量的数据集。首先,我们回顾关键的招募和留存技术,并指出各群体间保持一致性和包容性的重要性。其次,我们讨论减少家庭扫描焦虑的方法,以及通过描述预筛查过程、使用扫描仪模拟器以及关注参与者和家庭舒适度来提高扫描成功率的方法。最后,我们概述发育神经影像学中的几个重要设计考虑因素,例如提出适合发育阶段的问题、尽量减少数据丢失以及公共数据集的适用性。总之,我们希望本文能成为那些希望进入或更多了解发育认知神经科学领域的人的有用工具。