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印度尼西亚古邦市铁强化即食玉米的配方及其对解决青春期女孩贫血问题的效果

Formulation and Effect of Iron Fortified Instant Corn on Addressing Anemia among Adolescent Girls in Kupang, Indonesia.

作者信息

Gasong Ludia Simuruk, Damayanthi Evy, Marliyati Sri Anna, Martianto Drajat

机构信息

Department of Food Technology, Kupang State Agricultural Polytechnic, Kupang 85148, Indonesia.

Department of Community Nutrition, Faculty of Human Ecology, IPB University, Bogor 16680, Indonesia.

出版信息

Prev Nutr Food Sci. 2022 Sep 30;27(3):276-281. doi: 10.3746/pnf.2022.27.3.276.

Abstract

This study aimed to develop Fe-fortified instant Bose corn (IBC), a traditional Timorese food, as a strategy to address anemia among adolescent girls in Kupang, Indonesia. Instant corn and cowpea grits were made to shorten the preparation time with various times of soaking (IBC1=10 min; IBC2=15 min; IBC3=20 min) to select the best formula. The selected IBC was then fortified with NaFeEDTA·3HO and nutrient content was evaluated. In the intervention study, a pre-post controlled trial was applied to 40 anemic adolescent girls aged 16∼19 years. Subjects with severe anemia (Hb=8.5∼10.4 g/dL) received the fortified selected IBC, whereas those with moderate anemia (Hb=10.5∼11.5 g/dL) received the unfortified selected IBC. A total of 100 g IBC were provided three times/week for 2 months. The hemoglobin and soluble transferrin receptor (sTfR) levels were measured at baseline and endline, respectively. IBC3 produced the highest acceptance level as compared to other formulas. The fortified IBC3 met 127.4% recommended dietary allowances for iron. Moreover, both fortified and unfortified IBC3 significantly increased the hemoglobin levels of adolescent girls with the higher improvement found in the group of fortified IBC3 (1.73±1.21 g/dL; <0.05). However, the beneficial effects of the fortified IBC3 could not be observed on sTfR levels. Since the effect on Hb levels was significant with less effect, the intervention of IBC3 for only 2 months did not adequate to improve sTfR levels. Nevertheless, this study suggests that Fe-fortified IBC may be effective in preventing anemia among adolescent girls in Kupang, Indonesia.

摘要

本研究旨在开发铁强化即食博斯玉米(IBC),这是一种东帝汶传统食品,作为解决印度尼西亚古邦青春期女孩贫血问题的一项策略。制作即食玉米和豇豆粗粉以缩短制备时间,并设置不同浸泡时间(IBC1 = 10分钟;IBC2 = 15分钟;IBC3 = 20分钟)来选择最佳配方。然后用NaFeEDTA·3H₂O对选定的IBC进行强化,并评估其营养成分。在干预研究中,对40名年龄在16至19岁的贫血青春期女孩进行了前后对照试验。重度贫血(血红蛋白= 8.5至10.4 g/dL)的受试者接受强化后的选定IBC,而中度贫血(血红蛋白= 10.5至11.5 g/dL)的受试者接受未强化的选定IBC。每周提供三次共100克IBC,持续2个月。分别在基线和结束时测量血红蛋白和可溶性转铁蛋白受体(sTfR)水平。与其他配方相比,IBC3的接受度最高。强化后的IBC3满足了铁的膳食推荐摄入量的127.4%。此外,强化和未强化的IBC3均显著提高了青春期女孩的血红蛋白水平,强化IBC3组的改善更为明显(1.73±1.21 g/dL;P<0.05)。然而,强化IBC3对sTfR水平未观察到有益影响。由于对血红蛋白水平的影响显著但作用较小,仅2个月的IBC3干预不足以改善sTfR水平。尽管如此,本研究表明铁强化IBC可能对预防印度尼西亚古邦青春期女孩贫血有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbc6/9585402/49e24a5b0019/pnfs-27-3-276-f1.jpg

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