Mortazavi Seyed Alireza, Bevelacqua Joseph J, Welsh James S, Masoumi Seyed Jalil, Bahaaddini Beigy Zarandi Batool Faegheh, Ghadimi-Moghadam Abdolkarim, Haghani Masoud, Mortazavi Seyed Mohammad Javad
MD, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
PhD, Bevelacqua Resources, Richland, WA, United States.
J Biomed Phys Eng. 2022 Oct 1;12(5):539-542. doi: 10.31661/jbpe.v0i0.2110-1411. eCollection 2022 Oct.
An accumulating body of evidence shows that various ethnicities are differentially affected by SARS-COV-2 infection. Moreover, some evidence shows that due to the vaccine inequity and millions of people living with HIV, a major catastrophe could occur in African countries that possibly affects the whole world. Given the possibility that Neanderthal genes confer a slight increase in susceptibility, this difference, at least to some extent, might possibly decrease the risk of the emergence of new SARS-CoV-2 variants among black people in Africa. Recent studies show less death and fewer cases among the ethnic group classified as "Black Africans". Although Neanderthal DNA might explain some differences in morbidity and mortality of COVID-19, a multitude of confounders complicate things to where drawing definite conclusions is hard or even impossible. Using selective-pressure-free treatments (e.g. low dose radiotherapy) for COVID-19 pneumonia would be of crucial importance everywhere, but particularly in sub-Saharan Africa, where "long COVID" in millions of people with HIV paves the road for the more frequent emergence of new variants.
越来越多的证据表明，不同种族受新冠病毒感染的影响存在差异。此外，一些证据显示，由于疫苗分配不均以及数百万艾滋病毒感染者，非洲国家可能会发生一场重大灾难，甚至可能影响到整个世界。鉴于尼安德特人基因可能会使易感性略有增加，这种差异至少在一定程度上可能会降低非洲黑人中出现新冠病毒新变种的风险。最近的研究表明，在被归类为“非洲黑人”的种族群体中，死亡人数和病例数较少。尽管尼安德特人DNA可能解释了新冠病毒发病率和死亡率的一些差异，但众多混杂因素使情况变得复杂，以至于很难甚至不可能得出明确结论。对新冠肺炎肺炎使用无选择压力的治疗方法（如低剂量放疗）在各地都至关重要，尤其是在撒哈拉以南非洲地区，那里数百万艾滋病毒感染者的“长期新冠”为新变种更频繁出现铺平了道路。
