右大腿磷酸尿性间叶肿瘤：2例报告并文献复习
Phosphaturic mesenchymal tumor in right thigh: 2 cases report and literature review.
作者信息
Wang Ruifeng, Zhou Jiayu, Yu Yupei, Deng Junqi, Wu Ze, Ou Chunlin, Wu Yanhao, Yang Keda, Wang Junpu
机构信息
Department of Pathology, Xiang-ya Hospital, Central South University, Changsha City, Hunan Province, China.
Department of Pathology, School of Basic Medicine, Central South University, Changsha City, Hunan Province, China.
出版信息
Clin Pathol. 2022 Oct 21;15:2632010X221129588. doi: 10.1177/2632010X221129588. eCollection 2022 Jan-Dec.
BACKGROUND
Phosphaturic mesenchymal tumor (PMT) is a very rare tumor of bone and soft tissue that has no specific clinical manifestations. Here we present 2 cases of PMT in the right thigh, including comparatively adequate immunohistochemistry.
CASE PRESENTATION
We described 2 cases of PMT in the right thigh with manifestations of hypophosphatemia. PET-CT examination showed that both patients had lesions with increased expression of somatostatin receptors in the right thigh. Bland cells and dirty calcified stroma were exhibited under the microscope. And immunohistochemical detection of FGF-23 was positive.
CONCLUSIONS
PMT is a very uncommon tumor for which diagnosis and treatment are often delayed. Considering the importance of surgery for the treatment of this disease, a full understanding of its clinicopathological features will facilitate the diagnosis of this disease.
背景
磷酸尿性间叶肿瘤（PMT）是一种非常罕见的骨与软组织肿瘤，无特异性临床表现。在此我们报告2例右侧大腿的PMT病例，包括相对充分的免疫组化结果。
病例报告
我们描述了2例右侧大腿的PMT病例，表现为低磷血症。PET-CT检查显示，两名患者右侧大腿均有生长抑素受体表达增加的病变。显微镜下可见淡染细胞和污浊的钙化间质。FGF-23免疫组化检测呈阳性。
结论
PMT是一种非常罕见的肿瘤，其诊断和治疗常常延迟。考虑到手术治疗该病的重要性，全面了解其临床病理特征将有助于该病的诊断。
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