病例报告：使用镓- DOTATATE -PET指导复杂脑膜瘤疾病的治疗

Meißner Anna-Katharina, von Spreckelsen Niklas, Al Shughri Abdulkader, Brunn Anna, Fuertjes Gina, Schlamann Marc, Schmidt Matthias, Dietlein Markus, Rueß Daniel, Ruge Maximilian I, Galldiks Norbert, Goldbrunner Roland

Department of General Neurosurgery, Center for Neurosurgery, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.

Department of Neuropathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.

Front Oncol. 2022 Oct 12;12:1017339. doi: 10.3389/fonc.2022.1017339. eCollection 2022.

Currently, contrast-enhanced MRI is the method of choice for treatment planning and follow-up in patients with meningioma. However, positron emission tomography (PET) imaging of somatostatin receptor subtype 2 (SSTR2) expression using Ga-DOTATATE may provide a higher sensitivity for meningioma detection, especially in cases with complex anatomy or in the recurrent setting. Here, we report on a patient with a multilocal recurrent atypical meningioma, in which Ga-DOTATATE PET was considerably helpful for treatment guidance and decision-making.

目前，对比增强磁共振成像（MRI）是脑膜瘤患者治疗计划制定和随访的首选方法。然而，使用镓[68Ga] DOTATATE对生长抑素受体2型（SSTR2）表达进行正电子发射断层扫描（PET）成像，对脑膜瘤的检测可能具有更高的灵敏度，尤其是在解剖结构复杂或复发的情况下。在此，我们报告一例多部位复发的非典型脑膜瘤患者，其中镓[68Ga] DOTATATE PET对治疗指导和决策有很大帮助。