Silhadi Sabrina, Pinaud Simon Édouard, Nendaz Mathieu, Stirnemann Jérôme
Service de médecine interne générale, Hôpitaux universitaires de Genève, 1211 Genève 14.
Rev Med Suisse. 2022 Oct 26;18(801):2020-2023. doi: 10.53738/REVMED.2022.18.801.2020.
Vitamin B1 also known as thiamin is an essential vitamin assuring body functioning and comes exclusively from food. Vitamin B1 deficiency is an under-diagnosed disease because it is less frequently suspected in high income countries. However, its risk factors, like alcohol and malnutrition, are common in the general population. Thiamin deficiency can lead to three clinical entities, Gayet-Wernicke encephalopathy, which can progress to Korsakoff encephalopathy, wet Beriberi and its dry form. These diseases are associated with high mortality and heavy long-term sequelae. Rapid diagnosis enables timely treatment.
维生素B1也被称为硫胺素,是一种确保身体正常运转的必需维生素,且仅来源于食物。维生素B1缺乏症是一种诊断不足的疾病,因为在高收入国家较少被怀疑。然而,其风险因素,如酗酒和营养不良,在普通人群中很常见。硫胺素缺乏可导致三种临床病症,即可能进展为科萨科夫脑病的盖-韦脑病、湿性脚气病及其干性形式。这些疾病与高死亡率和严重的长期后遗症相关。快速诊断能够实现及时治疗。