Department of Experimental & Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.
Department of Pharmaceutical Care & Health Systems, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.
Pharmacogenomics. 2022 Nov;23(16):873-885. doi: 10.2217/pgs-2022-0094. Epub 2022 Oct 31.
To assess knowledge and attitudes toward pharmacogenomics (PGx) of incoming doctoral pharmacy students, to evaluate the internal structure and reliability of the PGx survey and to identify variables associated with the different responses. A PGx survey based on the core pharmacist competencies in PGx was created. Of 83.2% analyzable responses, 91% believed PGx is a useful tool and relevant to future practice but over 70% stated they lack confidence in clinical PGx knowledge. This 38-item PGx survey included three factors showing high reliability. Prior genetic/PGx testing and unsatisfactory medication experiences were associated with a more positive attitude toward PGx. The majority of students have positive attitudes toward PGx, but lack knowledge in genetic concepts and clinical PGx.
为了评估即将入读博士药学专业的学生对药物基因组学（PGx）的知识和态度，评估 PGx 调查的内部结构和可靠性，并确定与不同反应相关的变量。 基于 PGx 中核心药剂师能力，创建了一个 PGx 调查。 在可分析的 83.2%的反应中，91%的人认为 PGx 是一种有用的工具，与未来的实践相关，但超过 70%的人表示他们对临床 PGx 知识缺乏信心。 这个 38 项的 PGx 调查包括三个显示出高可靠性的因素。 先前的遗传/PGx 测试和不满意的药物治疗经历与对 PGx 的更积极态度相关。 大多数学生对 PGx 持积极态度，但缺乏遗传概念和临床 PGx 的知识。
