Alzheimers Dement. 2022 Nov;18(11):2375-2381. doi: 10.1002/alz.12837. Epub 2022 Oct 31.
Preliminary estimates suggest that current global health-care systems lack the resource capacity to provide persons with dementia timely access to diagnosis, treatment, and care. There is an increasing need to improve timely identification of individuals who will likely progress to Alzheimer's disease (AD) dementia particularly among under-represented, underserved, and vulnerable populations. The rapidly evolving area of bioinformatics of health system data and the emergence of fluid-based biomarkers for pre-symptomatic AD may provide an innovative strategic option for health system planners. A think-tank style meeting entitled "The Campaign to Prevent Alzheimer's Disease Work Group on Community-Based Detection and Assessment of Cognitive Decline" developed recommendations to guide future sustainability activities, public policy campaigns, and implementation pilots. The group identified and explored different pathways of community-based detection using electronic health records, from different international health-care systems, to detect and surveil individuals with early possible cognitive impairment.
初步估计表明,当前的全球卫生保健系统缺乏为痴呆患者提供及时诊断、治疗和护理的资源能力。越来越有必要及时识别可能发展为阿尔茨海默病(AD)痴呆的个体,特别是在代表性不足、服务不足和弱势群体中。健康系统数据的生物信息学领域的迅速发展以及针对 AD 进行无症状期的液体生物标志物的出现,为健康系统规划者提供了一个创新的战略选择。一个名为“预防阿尔茨海默病运动工作组:基于社区的认知衰退检测和评估”的智囊团风格会议制定了建议,以指导未来的可持续性活动、公共政策运动和实施试点。该小组确定并探讨了利用电子健康记录,从不同国际卫生保健系统中,检测和监测早期可能存在认知障碍的个体的不同社区检测途径。