Häussler Daniel, Hüttemann Stefanie, Brom Jörn, Rotter Nicole, Sadick Haneen
Department of Otorhinolaryngology Head and Neck Surgery, University Hospital Mannheim, Ruprecht-Karls-Universität Heidelberg, Heidelberg, Germany.
Brom Epithetics, Heidelberg, Germany.
Ear Nose Throat J. 2025 Aug;104(8):486-492. doi: 10.1177/01455613221133202. Epub 2022 Oct 31.
The treatment of auricular keloids is challenging, as they tend to recur; further, the treatment may impact quality of life and implies cosmetic and functional impairment for each patient. There is no standardized therapeutic concept established, and the literature is lacking long-term results of available treatment modalities. Patients suffering from auricular keloids were included in the study. All patients had undergone surgical resection, intralesional injection of triamcinolone acetonide (TAC), and the application of an individual pressure splint. Quality of life (QoL) was assessed using the keloid intervention benefit inventory 21 (KIBI-21). Further analysis was carried out for patients without (group 1) and with (group 2) recurrence of the keloid. In total, 50 keloids with a mean follow-up period of 59 months (range 6-137 months) could be analyzed. In nine cases (18%), a keloid recurrence was found during the observation period. The assessment of QoL differed significantly between study groups at = 0.04, as well as for the subcategories General Health (GH) and Physical Health (PH). No differences were found for the categories Social Impact (SI) and Self-Esteem (SE). The multimodal subsequent treatment regimen consisting of surgical resection, intralesional TAC injection, and the application of an individual magnetic pressure splint shows good results concerning long-term recurrence rates. The treatment method shows positive effects on the QoL, especially in the measured categories GH and PH.
耳廓瘢痕疙瘩的治疗具有挑战性，因为它们容易复发；此外，治疗可能会影响生活质量，并对每位患者造成外观和功能损害。目前尚未建立标准化的治疗理念，而且文献中缺乏现有治疗方式的长期效果。患有耳廓瘢痕疙瘩的患者被纳入该研究。所有患者均接受了手术切除、曲安奈德（TAC）病灶内注射以及个性化压力夹板治疗。使用瘢痕疙瘩干预效益量表21（KIBI - 21）评估生活质量（QoL）。对瘢痕疙瘩未复发的患者（第1组）和复发的患者（第组）进行了进一步分析。总共分析了50个瘢痕疙瘩，平均随访期为59个月（范围6 - 137个月）。在观察期内发现9例（18%）瘢痕疙瘩复发。在α = 0.04时，研究组之间的生活质量评估以及“总体健康”（GH）和“身体健康”（PH）子类别存在显著差异。在“社会影响”（SI）和“自尊”（SE）类别中未发现差异。由手术切除、病灶内TAC注射和个性化磁性压力夹板组成的多模式后续治疗方案在长期复发率方面显示出良好效果。该治疗方法对生活质量有积极影响，尤其是在测量的GH和PH类别中。
