从中年到老年饮食质量变化与健康老龄化的关系：新加坡华人健康研究。

Association between changes in diet quality from mid-life to late-life and healthy ageing: the Singapore Chinese Health Study.

机构信息

Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Singapore Institute for Clinical Sciences, Agency for Science, Technology, and Research, Singapore, Singapore.

出版信息

Age Ageing. 2022 Oct 6;51(10). doi: 10.1093/ageing/afac232.

DOI:10.1093/ageing/afac232

PMID:36315430

Abstract

BACKGROUND

Few studies have evaluated the association between changes in diet quality from mid-life to late-life and healthy ageing.

METHODS

We included 12,316 Chinese adults aged 45-74 years at baseline (1993-1998) from the Singapore Chinese Health Study. Diet quality was measured using the Dietary Approaches to Stop Hypertension (DASH) scores at baseline and follow-up 3 interviews (2014-2016). Healthy ageing was assessed at follow-up 3 interviews, and was defined as absence of specific chronic diseases, good mental and overall self-perceived health, good physical functioning and absence of cognitive impairment, limitations in instrumental activities of daily living or function-limiting pain. Multivariable-adjusted logistic regression models were applied to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for the association between changes in DASH scores and healthy ageing.

RESULTS

Compared with participants who maintained relatively stable DASH scores, a >10% decrease in DASH score was associated with a 16% (95% CI, 4-26%) lower likelihood of healthy ageing, whereas a >10% increase in DASH score was associated with a 19% (95% CI, 3-37%) higher likelihood of healthy ageing. Compared with participants who were in the low-score group consistently, participants who increased their DASH scores from moderate-score at baseline to high-score at follow-up 3 had a 53% (95% CI, 21-92%) higher likelihood of healthy ageing, whereas those who were in the high-score group consistently had 108% (95% CI, 71-152%) higher likelihood of healthy ageing.

CONCLUSIONS

Improving diet quality from mid- to late-life was associated with a higher likelihood of healthy ageing.

摘要

背景

很少有研究评估从中年到晚年饮食质量的变化与健康衰老之间的关系。

方法

我们纳入了 12316 名年龄在 45-74 岁的新加坡华人健康研究中的中国成年人，他们在基线（1993-1998 年）和随访的 3 次访谈（2014-2016 年）时接受了饮食质量的评估。采用高血压膳食方法（DASH）评分来评估饮食质量。在随访的 3 次访谈中评估健康衰老，定义为没有特定的慢性疾病、良好的精神和整体自我感知健康、良好的身体功能和没有认知障碍、日常生活活动工具受限或功能受限的疼痛。应用多变量调整的逻辑回归模型来估计 DASH 评分变化与健康衰老之间的关联的比值比（OR）和 95%置信区间（CI）。

结果

与维持相对稳定的 DASH 评分的参与者相比，DASH 评分下降超过 10%与健康衰老的可能性降低 16%（95%CI，4-26%）相关，而 DASH 评分增加超过 10%与健康衰老的可能性增加 19%（95%CI，3-37%）相关。与始终处于低评分组的参与者相比，基线时处于中评分组但在随访 3 时增加到高评分组的参与者健康衰老的可能性增加 53%（95%CI，21-92%），而始终处于高评分组的参与者健康衰老的可能性增加 108%（95%CI，71-152%）。