Suppr超能文献

子宫动脉栓塞联合超声引导下扩宫刮宫术治疗剖宫产瘢痕妊娠:疗效及5至8年随访研究

Uterine artery embolization combined with ultrasound-guided dilation and curettage for the treatment of cesarean scar pregnancy: Efficacy and 5-8-year follow-up study.

作者信息

Gu Zhuxin, Jia Pengfei, Gao Ziyang, Gu Weiwei, Zhao Hui, Zhao Suming

机构信息

Department of Interventional Radiology,affiliated Hospital of Nantong University, Nantong, 226000, Jiangsu, China.

Department of Digital Subtraction Angiography,affiliated Hospital of Nantong University, Nantong, 226000, Jiangsu, China.

出版信息

J Interv Med. 2022 Mar 18;5(3):148-152. doi: 10.1016/j.jimed.2022.03.006. eCollection 2022 Aug.

Abstract

OBJECTIVE

To evaluate the efficacy and safety of uterine artery embolization (UAE) combined with dilation and curettage (D&C) using ultrasound as a treatment for cesarean scar pregnancy (CSP) and assess its effect on ovarian and reproductive function.

METHODS

A total of 54 patients with uterine CSP between January 2011 and December 2015 were included in this retrospective study. The patients were treated with UAE combined with D&C using ultrasound for the treatment of CSP and followed up for 5-8 years. Their medical records, medical histories, clinical manifestations, treatment courses, and treatment results were analyzed.

RESULTS

The 54 patients were initially treated without severe complications. β-Human chorionic gonadotropin (β-hCG) normalization took 36.11 ​± ​10.73 days (range, 25-84 days), length of hospitalization was 6.6 ​± ​1.5 days (range, 4-10 days), and total blood loss was 18.48 ​± ​8.41 ​mL (range, 5-33 ​mL). All patients resumed normal menstruation after 33.48 ​± ​8.71 days (range, 26-70 days). At the 5-8-year follow-up after UAE combined with D&C by ultrasound for the treatment of uterine CSP, the menstrual volume in 32 (59.3%) patients decreased versus before the operation. Compared with pretreatment, the menstrual cycle was prolonged in two (3.7%) cases, shortened in 10 (18.5%) cases, irregular in one (1.9%) case, and unchanged in 39 (72.2%) cases. Three patients conceived naturally and successfully gave birth to healthy children. Seven (12.96%) patients with accidental natural pregnancies chose induced abortion with no significant change in their sex lives.

CONCLUSION

UAE combined with D&C using ultrasound for the treatment of uterine CSP is safe and effective and may not affect the fertility of patients aged <40 years. However, menstrual volume may be reduced in some patients.

摘要

目的

评估子宫动脉栓塞术(UAE)联合超声引导下刮宫术(D&C)治疗剖宫产瘢痕妊娠(CSP)的疗效和安全性,并评估其对卵巢及生殖功能的影响。

方法

本回顾性研究纳入了2011年1月至2015年12月期间共54例子宫CSP患者。患者接受UAE联合超声引导下D&C治疗CSP,并进行了5至8年的随访。分析了他们的病历、病史、临床表现、治疗过程和治疗结果。

结果

54例患者初始治疗时无严重并发症。β-人绒毛膜促性腺激素(β-hCG)恢复正常需36.11±10.73天(范围25 - 84天),住院时间为6.6±1.5天(范围4 - 10天),总失血量为18.48±8.41 mL(范围5 - 33 mL)。所有患者在33.48±8.71天(范围26 - 70天)后恢复正常月经。在UAE联合超声引导下D&C治疗子宫CSP后的5至8年随访中,32例(59.3%)患者的月经量较术前减少。与治疗前相比,2例(3.7%)患者月经周期延长,10例(18.5%)患者月经周期缩短,1例(1.9%)患者月经周期不规律,39例(72.2%)患者月经周期无变化。3例患者自然受孕并成功产下健康婴儿。7例(12.96%)意外自然受孕的患者选择人工流产,其性生活无明显变化。

结论

UAE联合超声引导下D&C治疗子宫CSP安全有效,可能不影响40岁以下患者的生育能力。然而,部分患者的月经量可能会减少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e15/9617151/0295800a8c0f/gr1.jpg

相似文献

2
Reproductive outcomes of cesarean scar pregnancies treated with uterine artery embolization combined with curettage.
Taiwan J Obstet Gynecol. 2022 Jul;61(4):601-605. doi: 10.1016/j.tjog.2021.08.005.
3
Uterine Artery Embolization Combined with Dilation and Curettage for the Treatment of Cesarean Scar Pregnancy: Efficacy and Future Fertility.
Cardiovasc Intervent Radiol. 2018 Aug;41(8):1165-1173. doi: 10.1007/s00270-018-1934-z. Epub 2018 Mar 15.
5
The novel use of lauromacrogol: A respective study of ultrasound-guided sclerosant injection for cesarean scar pregnancy.
J Obstet Gynaecol Res. 2022 Jan;48(1):140-145. doi: 10.1111/jog.15080. Epub 2021 Nov 9.
10
[Cesarean scar pregnancy analysis of 42 cases].
Zhonghua Fu Chan Ke Za Zhi. 2009 Aug;44(8):566-9.

引用本文的文献

本文引用的文献

1
Clinical investigation of fertility after uterine artery embolization.
Am J Obstet Gynecol. 2021 Oct;225(4):403.e1-403.e22. doi: 10.1016/j.ajog.2021.05.033. Epub 2021 May 29.
2
[Correlation between uterine scar condition and uterine rupture for pregnancy women after previous cesarean section].
Zhonghua Fu Chan Ke Za Zhi. 2019 Jun 25;54(6):375-380. doi: 10.3760/cma.j.issn.0529-567x.2019.06.004.
3
Updates on Uterine Artery Embolization.
Semin Intervent Radiol. 2018 Mar;35(1):48-55. doi: 10.1055/s-0038-1636521. Epub 2018 Apr 5.
4
Anti-Müllerian hormone levels before and after uterine artery embolization.
Minim Invasive Ther Allied Technol. 2018 Jun;27(3):186-190. doi: 10.1080/13645706.2017.1365728. Epub 2017 Sep 6.
5
Comparison of three treatment strategies for cesarean scar pregnancy.
Arch Gynecol Obstet. 2017 Aug;296(2):383-389. doi: 10.1007/s00404-017-4426-5. Epub 2017 Jun 20.
6
The Treatment of Cesarean Scar Pregnancy with Uterine Artery Embolization and Curettage as Compared to Transvaginal Hysterotomy.
Eur J Obstet Gynecol Reprod Biol. 2017 Jul;214:44-49. doi: 10.1016/j.ejogrb.2017.04.032. Epub 2017 Apr 20.
7
Cesarean Scar Pregnancy: A Systematic Review.
J Minim Invasive Gynecol. 2017 Jul-Aug;24(5):731-738. doi: 10.1016/j.jmig.2017.02.020. Epub 2017 Mar 6.
9
The effects of uterine artery embolization on ovarian reserve.
Eur J Obstet Gynecol Reprod Biol. 2016 Nov;206:172-176. doi: 10.1016/j.ejogrb.2016.09.001. Epub 2016 Sep 23.
10
Curettage after uterine artery embolization combined with methotrexate treatment for caesarean scar pregnancy.
Exp Ther Med. 2016 Sep;12(3):1469-1475. doi: 10.3892/etm.2016.3489. Epub 2016 Jun 29.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验