Gu Zhuxin, Jia Pengfei, Gao Ziyang, Gu Weiwei, Zhao Hui, Zhao Suming
Department of Interventional Radiology,affiliated Hospital of Nantong University, Nantong, 226000, Jiangsu, China.
Department of Digital Subtraction Angiography,affiliated Hospital of Nantong University, Nantong, 226000, Jiangsu, China.
J Interv Med. 2022 Mar 18;5(3):148-152. doi: 10.1016/j.jimed.2022.03.006. eCollection 2022 Aug.
To evaluate the efficacy and safety of uterine artery embolization (UAE) combined with dilation and curettage (D&C) using ultrasound as a treatment for cesarean scar pregnancy (CSP) and assess its effect on ovarian and reproductive function.
A total of 54 patients with uterine CSP between January 2011 and December 2015 were included in this retrospective study. The patients were treated with UAE combined with D&C using ultrasound for the treatment of CSP and followed up for 5-8 years. Their medical records, medical histories, clinical manifestations, treatment courses, and treatment results were analyzed.
The 54 patients were initially treated without severe complications. β-Human chorionic gonadotropin (β-hCG) normalization took 36.11 ± 10.73 days (range, 25-84 days), length of hospitalization was 6.6 ± 1.5 days (range, 4-10 days), and total blood loss was 18.48 ± 8.41 mL (range, 5-33 mL). All patients resumed normal menstruation after 33.48 ± 8.71 days (range, 26-70 days). At the 5-8-year follow-up after UAE combined with D&C by ultrasound for the treatment of uterine CSP, the menstrual volume in 32 (59.3%) patients decreased versus before the operation. Compared with pretreatment, the menstrual cycle was prolonged in two (3.7%) cases, shortened in 10 (18.5%) cases, irregular in one (1.9%) case, and unchanged in 39 (72.2%) cases. Three patients conceived naturally and successfully gave birth to healthy children. Seven (12.96%) patients with accidental natural pregnancies chose induced abortion with no significant change in their sex lives.
UAE combined with D&C using ultrasound for the treatment of uterine CSP is safe and effective and may not affect the fertility of patients aged <40 years. However, menstrual volume may be reduced in some patients.
评估子宫动脉栓塞术(UAE)联合超声引导下刮宫术(D&C)治疗剖宫产瘢痕妊娠(CSP)的疗效和安全性,并评估其对卵巢及生殖功能的影响。
本回顾性研究纳入了2011年1月至2015年12月期间共54例子宫CSP患者。患者接受UAE联合超声引导下D&C治疗CSP,并进行了5至8年的随访。分析了他们的病历、病史、临床表现、治疗过程和治疗结果。
54例患者初始治疗时无严重并发症。β-人绒毛膜促性腺激素(β-hCG)恢复正常需36.11±10.73天(范围25 - 84天),住院时间为6.6±1.5天(范围4 - 10天),总失血量为18.48±8.41 mL(范围5 - 33 mL)。所有患者在33.48±8.71天(范围26 - 70天)后恢复正常月经。在UAE联合超声引导下D&C治疗子宫CSP后的5至8年随访中,32例(59.3%)患者的月经量较术前减少。与治疗前相比,2例(3.7%)患者月经周期延长,10例(18.5%)患者月经周期缩短,1例(1.9%)患者月经周期不规律,39例(72.2%)患者月经周期无变化。3例患者自然受孕并成功产下健康婴儿。7例(12.96%)意外自然受孕的患者选择人工流产,其性生活无明显变化。
UAE联合超声引导下D&C治疗子宫CSP安全有效,可能不影响40岁以下患者的生育能力。然而,部分患者的月经量可能会减少。