Cai Tianhong, Zhang Rong, Chen Kai, Deng Ting, Zhan Tenghui
Vascular Surgery & Interventional Therapy Department, Fujian Maternity and Child Health Hospital, Fuzhou, China.
College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Pain Manag. 2025 Jun;15(6):325-332. doi: 10.1080/17581869.2025.2511464. Epub 2025 May 26.
Uterine artery embolization (UAE) for cesarean scar pregnancy (CSP) can cause significant pain.
To evaluate safety and efficacy of intra-arterial lidocaine during UAE for CSP.
Retrospective study of 255 CSP patients: Control Group (184) without lidocaine; Study Group I (39) with unilateral lidocaine; Study Group II (32) with bilateral lidocaine. Outcomes included VAS pain scores and morphine usage.
Early postoperative VAS scores (0-2 hours) were significantly lower in study groups ( < 0.001). No differences in later VAS scores (4-24 hours), maximal VAS scores, morphine dosage, or safety indicators.
Intra-arterial lidocaine during UAE for CSP provides effective analgesia immediately post-procedure but only for the first 2-4 hours, without reducing overall opioid requirements.
剖宫产瘢痕妊娠（CSP）行子宫动脉栓塞术（UAE）可引起明显疼痛。
评估在CSP的UAE过程中动脉内注射利多卡因的安全性和有效性。
对255例CSP患者进行回顾性研究：对照组（184例）未使用利多卡因；研究组I（39例）单侧使用利多卡因；研究组II（32例）双侧使用利多卡因。观察指标包括视觉模拟评分法（VAS）疼痛评分和吗啡用量。
研究组术后早期（0 - 2小时）VAS评分显著更低（<0.001）。后期VAS评分（4 - 24小时）、最大VAS评分、吗啡用量或安全指标无差异。
CSP的UAE过程中动脉内注射利多卡因在术后即刻可提供有效的镇痛作用，但仅持续2 - 4小时，且不降低总体阿片类药物需求量。
