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辐射与中枢神经系统效应:辐射研究学会最近一次研讨会证据摘要。

Radiation and CNS effects: summary of evidence from a recent symposium of the Radiation Research Society.

机构信息

Department of Epidemiology and Biostatistics, School of Medicine, University of California, San Francisco, San Francisco, CA, USA.

Environment and Lifestyle Epidemiology Branch, International Agency for Research on Cancer, Lyon, France.

出版信息

Int J Radiat Biol. 2023;99(9):1332-1342. doi: 10.1080/09553002.2023.2142984. Epub 2022 Nov 11.

Abstract

This article summarizes a Symposium on 'Radiation risks of the central nervous system' held virtually at the 67th Annual Meeting of the Radiation Research Society, 3-6 October 2021. Repeated low-dose radiation exposure over a certain period could lead to reduced neuronal proliferation, altered neurogenesis, neuroinflammation and various neurological complications, including psychological consequences, necessitating further research in these areas. Four speakers from radiation biology, genetics and epidemiology presented the latest data from their studies seeking insights into this important topic. This symposium highlighted new and important directions for further research on mental health disorders, neurodegenerative conditions and cognitive impairment. Future studies will examine risks of mental and behavioral disorders and neurodegenerative diseases following protracted radiation exposures to better understand risks of occupational exposures as well as provide insights into risks from exposures to galactic cosmic rays.

摘要

本文总结了 2021 年 10 月 3 日至 6 日在第 67 届放射研究学会年会上以虚拟方式举行的“中枢神经系统辐射风险”研讨会。在一定时期内反复接受低剂量辐射可能会导致神经元增殖减少、神经发生改变、神经炎症和各种神经并发症,包括心理后果,需要在这些领域进一步研究。来自放射生物学、遗传学和流行病学的四位演讲者展示了他们研究的最新数据,以深入了解这一重要课题。本次研讨会强调了进一步研究心理健康障碍、神经退行性疾病和认知障碍的新的和重要方向。未来的研究将研究长期辐射暴露后精神和行为障碍以及神经退行性疾病的风险,以更好地了解职业暴露的风险,并深入了解来自银河宇宙射线暴露的风险。

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