Experimental Biomedicine and Clinical Neurosciences, School of Medicine, Postgraduate Residency Program in Neurological Surgery, Neurosurgical Clinic, University of Palermo, Palermo, Italy.
Department of Neurosurgery, Garibaldi Hospital, Catania, Italy
BMJ Case Rep. 2022 Nov 1;15(11):e252451. doi: 10.1136/bcr-2022-252451.
Purely calvarial or intradiploic cavernous haemangiomas (PICHs) are rare benign tumours accounting for 0.2% of all bone tumours and 10% of benign skull tumours. They are generally small, slow-growing and asymptomatic lesions. Here the authors described an immunocompromised patient with concomitant giant intradiploic ossified globular cavernous angioma and multifocal neurotoxoplasmosis that underwent a combined approach to treat both lesions with an en-bloc resection of the right parietal intradiploic lesion and biopsy of the left occipital subcortical lesion.Indeed, it is essential to exclude the presence of metastases by making a timely differential diagnosis. En-bloc surgical resection of purely intradiploic ossified cavernous angioma is the gold standard treatment and the prognosis after a complete excision is usually excellent with rarer recurrence rate.
单纯颅盖或硬脑膜内海绵状血管瘤(PICHs)是罕见的良性肿瘤,占所有骨肿瘤的 0.2%,占良性颅骨肿瘤的 10%。它们通常是小的、生长缓慢的、无症状的病变。在这里,作者描述了一例免疫功能低下的患者,同时患有巨大硬脑膜内骨化球形海绵状血管畸形和多发性神经弓形虫病,采用联合方法治疗两种病变,整块切除右侧顶骨硬脑膜内病变,并对左侧枕叶皮质下病变进行活检。事实上,通过及时鉴别诊断排除转移的存在是至关重要的。整块切除单纯硬脑膜内骨化海绵状血管瘤是金标准治疗方法,完全切除后的预后通常很好,复发率较低。