Voropaeva S D, Sokolova I E, Emel'ianova A I
Antibiot Med Biotekhnol. 1987 Jun;32(6):449-53.
The study revealed the dominating role of aerobic-anaerobic microbial associations and in particular the specific role of anaerobic gram positive cocci in development of puerperal endometritis. The data suggested that a definite level of the uterus cavity contamination with microbes, not lower than 10(4)-10(5) CFU/ml or a large number of bacterial associates, not less than 3 was necessary for endometritis development. It was confirmed that pathogenicity of anaerobes increased in the presence of aerobic bacteria. It is concluded that quantitative methods for detecting the main causative agents of endometritis are needed. A set of antibacterial drugs for rational antibacterial therapy of puerperal endometritis is recommended.
该研究揭示了需氧 - 厌氧微生物联合体的主导作用,尤其是厌氧革兰氏阳性球菌在产褥期子宫内膜炎发展中的特定作用。数据表明,子宫腔微生物污染达到一定水平,不低于10⁴ - 10⁵CFU/ml,或存在大量细菌联合体,不少于3种,对于子宫内膜炎的发展是必要的。已证实厌氧菌在需氧菌存在时致病性增强。得出结论,需要有定量方法来检测子宫内膜炎的主要病原体。推荐了一组用于产褥期子宫内膜炎合理抗菌治疗的抗菌药物。