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脑型并殖吸虫病致痴呆。

Cerebral Paragonimiasis Presenting with Dementia.

机构信息

Department of Psychiatry, Research Institute of Medical Science, College of Medicine, Konkuk University, Chungju 27376, Korea.

出版信息

Korean J Parasitol. 2022 Oct;60(5):353-355. doi: 10.3347/kjp.2022.60.5.353. Epub 2022 Oct 21.

Abstract

We report a case of an 80-year-old Korean man with chronic cerebral paragonimiasis who presented with progressive memory impairment. He suffered from pulmonary paragonimiasis 60 years ago and has been experiencing epilepsy since the age of 45. He began experiencing memory and cognitive deterioration 3 years ago. He visited the neuropsychiatric department of our hospital to check his symptoms and health from a year ago. Contrast-enhanced brain magnetic resonance imaging study revealed calcifications and cystic lesions encompassing the right temporo-occipital region. Encephalomalatic changes were also observed in the right occipital and temporal areas. The anti-Paragonimus specific IgG antibodies in his serum showed a strong positive response. The neuropsychological test results showed a Global Deterioration Scale of 4 and a Clinical Dementia Rating Scale of 1. The chronic cerebral paragonimiasis lesions in the patient's right temporo-occipital region might induce the dementic change.

摘要

我们报告了一例 80 岁韩国男性慢性脑并殖吸虫病病例,该患者表现为进行性记忆障碍。他在 60 年前患有肺并殖吸虫病,从 45 岁开始患有癫痫。他在 3 年前开始出现记忆和认知功能下降。他因一年前的症状和健康问题前往我们医院的神经精神科就诊。增强脑磁共振成像研究显示,右颞枕区有钙化和囊状病变。右枕叶和颞叶也观察到脑软化改变。他血清中的抗并殖吸虫特异性 IgG 抗体呈强阳性反应。神经心理学测试结果显示总体衰退量表得分为 4,临床痴呆评定量表得分为 1。患者右侧颞枕区的慢性脑并殖吸虫病病变可能导致痴呆变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c265/9633155/953904cfa1a6/kjp-60-5-353f1.jpg

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