Hong Sheng-Bo, Liang Lan-Chang
Department of Chemistry, National Sun Yat-sen University Kaohsiung 80424 Taiwan
Department of Medicinal and Applied Chemistry, Kaohsiung Medical University Kaohsiung 80708 Taiwan.
RSC Adv. 2022 Oct 11;12(44):28862-28866. doi: 10.1039/d2ra05230j. eCollection 2022 Oct 4.
The catalytic activity of [(PhP--CH)N]PdCl in aerobic aqueous Suzuki couplings is described. Though hydrophobic, this molecular catalyst is competent in cross-coupling reactions of arylboronic acids with a variety of electronically activated, unactivated, and deactivated aryl iodides, bromides, and chlorides upon heating in aqueous solutions under aerobic conditions to give biphenyl derivatives without the necessity of amphiphiles even in the presence of an excess amount of mercury.
描述了[(PhP--CH)N]PdCl在有氧水相铃木偶联反应中的催化活性。尽管这种分子催化剂具有疏水性，但在有氧条件下于水溶液中加热时，它能够使芳基硼酸与各种电子活化、未活化和钝化的芳基碘化物、溴化物和氯化物发生交叉偶联反应，生成联苯衍生物，即使在存在过量汞的情况下也无需两亲试剂。
