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毒液及中毒症状的种内差异。

Intraspecific differences in venom and envenomation symptoms.

作者信息

Safdarian Mehdi, Vazirianzadeh Babak, Ghorbani Ahmad, Pashmforoosh Narges, Baradaran Masoumeh

机构信息

Nanotechnology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Social Determinant of Health Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

出版信息

EXCLI J. 2022 Sep 21;21:1222-1230. doi: 10.17179/excli2022-5078. eCollection 2022.

Abstract

Envenomation by is very frequent in Iran, especially in the south-west This scorpion is one of the six scorpions whose venom is used to prepare anti-venom. Using HPLC, we discovered venom components of varies from one specimen to another depending on geographical location, and this result is confirmed by those first found in various symptoms of sting in envenomed persons from two separate geographical places (north and south of Khuzestan province). There was a significant relationship between symptoms and location of envenomation by . Muscle spasm was more dominant in envenomed people from Northern cities, and venom chromatogram analysis showed the presence of at least six main sharp peaks in Northern rather than Southern . It shows intraspecific differences in venom of that must be considered in treatment of stung people from different geographical locations as well as in the preparation of anti-venom. See also Figure 1(Fig. 1).

摘要

在伊朗,尤其是西南部地区,[蝎子名称未给出]蜇伤极为常见。这种蝎子是六种其毒液被用于制备抗蛇毒血清的蝎子之一。通过高效液相色谱法,我们发现[蝎子名称未给出]的毒液成分因标本所处地理位置不同而存在差异,这一结果也得到了来自胡齐斯坦省两个不同地理位置(北部和南部)被蜇伤者不同症状的印证。[蝎子名称未给出]蜇伤的症状与蜇伤地点之间存在显著关联。肌肉痉挛在北部城市的被蜇伤者中更为常见,毒液色谱分析显示北部[蝎子名称未给出]毒液中至少有六个主要尖峰,而南部的则不然。这表明[蝎子名称未给出]毒液存在种内差异,在治疗来自不同地理位置的蜇伤者以及制备抗蛇毒血清时都必须予以考虑。另见图1(图1)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f25/9618731/b8318dce350a/EXCLI-21-1222-t-001.jpg

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