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苏联两个地区长寿人群及不同年龄段人群中1号、9号、16号染色体和Y染色体异染色质区域的多态性。

Polymorphism of heterochromatin areas on chromosomes 1, 9, 16 and Y in long-lived subjects and persons of different ages in two regions of the Soviet Union.

作者信息

Kuznetsova S M

出版信息

Arch Gerontol Geriatr. 1987 Jul;6(2):177-86. doi: 10.1016/0167-4943(87)90010-0.

DOI:10.1016/0167-4943(87)90010-0
PMID:3632129
Abstract

Variants of chromosome polymorphism were analyzed in long-lived individuals and in subjects aged 40-79 years (170 persons) in two regions of the Soviet Union. The results of this analysis allow the suggestion that there is an association between the individual variants of chromosome polymorphism as regards C heterochromatin and the longevity phenomenon. Large size C segments on the human Y chromosome and the long Y chromosome were found both in the Ukrainian and Abkhasian long-lived males. In the long-lived females the chromosome polymorphism variants were associated with a region of their residence. The long-lived females of Abkhasia had a decreased relative size of C segments on chromosome 1 and an increased absolute and relative size of C segments on chromosome 9, while in their Ukrainian counterparts there was an increased relative size of C segments on chromosome 1 and a decreased one on chromosome 16.

摘要

在苏联两个地区,对长寿个体以及40 - 79岁的受试者(共170人)的染色体多态性变异进行了分析。该分析结果表明,就C异染色质而言,染色体多态性的个体变异与长寿现象之间存在关联。在乌克兰和阿布哈兹的长寿男性中均发现了人类Y染色体上的大尺寸C区段以及长Y染色体。在长寿女性中,染色体多态性变异与她们的居住地区有关。阿布哈兹的长寿女性1号染色体上C区段的相对大小减小,9号染色体上C区段的绝对大小和相对大小增加,而她们的乌克兰同龄女性1号染色体上C区段的相对大小增加,16号染色体上的相对大小减小。

相似文献

1
Polymorphism of heterochromatin areas on chromosomes 1, 9, 16 and Y in long-lived subjects and persons of different ages in two regions of the Soviet Union.苏联两个地区长寿人群及不同年龄段人群中1号、9号、16号染色体和Y染色体异染色质区域的多态性。
Arch Gerontol Geriatr. 1987 Jul;6(2):177-86. doi: 10.1016/0167-4943(87)90010-0.
2
[Polymorphism of heterochromatin regions of chromosomes 1, 9, 16 and Y in long-lived persons and in persons of various ages from 2 areas of the Soviet Union].[苏联两个地区长寿者及不同年龄段人群中1、9、16号染色体和Y染色体异染色质区域的多态性]
Tsitol Genet. 1986 Nov-Dec;20(6):409-16.
3
[Heteromorphism of chromosome 1, 9 and 16 homologs in persons living in regions differing in the level of longevity].
Tsitol Genet. 1988 Jul-Aug;22(4):27-32.
4
[Quantitative analysis of C-segments of chromosomes 1, 9, 16 and Y in couples with reproductive disorders].[对患有生殖障碍的夫妇的1号、9号、16号染色体和Y染色体C区段的定量分析]
Genetika. 1987 Mar;23(3):540-3.
5
Heterochromatin is not an adequate explanation for close proximity of interphase chromosomes 1--Y, 9--Y, and 16--Y in human spermatozoa.异染色质并不能充分解释人类精子中1号染色体与Y染色体、9号染色体与Y染色体以及16号染色体与Y染色体在间期的紧密靠近现象。
Exp Cell Res. 2001 May 1;265(2):283-7. doi: 10.1006/excr.2001.5193.
6
Chromosomal polymorphisms of 1, 9, 16, and Y in 4 major ethnic groups: a large prenatal study.四个主要民族中1号、9号、16号染色体及Y染色体的多态性:一项大型产前研究
Am J Med Genet. 1987 Jan;26(1):95-101. doi: 10.1002/ajmg.1320260116.
7
Constitutive heterochromatin polymorphisms in children with acute lymphoblastic leukemia.
Pediatr Hematol Oncol. 1993 Jan-Mar;10(1):7-11. doi: 10.3109/08880019309016522.
8
[Analysis of the inheritance of heterochromatic regions in human chromosomes 1, 9, 16 and Y].[人类1号、9号、16号染色体及Y染色体异染色质区域的遗传分析]
Tsitol Genet. 1987 Sep-Oct;21(5):339-43.
9
[Polymorphism of the C-band segments of chromosomes 1, 9 and 16 in the peripheral blood lymphocytes of patients with endometrial cancer].[子宫内膜癌患者外周血淋巴细胞中1、9和16号染色体C带区段的多态性]
Tsitol Genet. 1993 Jul-Aug;27(4):66-71.
10
[Heterochromatic regions and the nondisjunction of human chromosome 21. I. Polymorphism of the C-bands of chromosomes 1, 9 and 16 in children with Down's syndrome].[异染色质区与人类21号染色体不分离。I. 唐氏综合征患儿1、9和16号染色体C带的多态性]
Tsitologiia. 1987 Jun;29(6):711-4.

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