Wu Yueran, Wang Xiangnan, Yin Zhenzhen, Dong Jiajia
College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China; College of Food Science and Technology, Nanjing Agricultural University, 210095 Nanjing, Jiangsu, China.
College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China; Key Research Laboratory of Chinese Medicine Processing of Jiangsu Province, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Food Chem. 2023 Mar 15;404(Pt B):134308. doi: 10.1016/j.foodchem.2022.134308. Epub 2022 Sep 19.
We report for the first time that curcumin is successfully encapsulated into a new natural pre-formed carrier, which was derived from arthrospore cell wall particles (APs) of probiotic Geotrichum candidum LG-8 and mainly composed of beta-1,4-glucan. Vacuum infusion process was used for efficient encapsulation of curcumin. The results showed that the encapsulation efficiency and yield of APs were 36.5 ± 0.9 % and 730.6 ± 26.5 μg/g (wet basis), respectively. Compared with the other probiotic carriers such as Saccharomyces cerevisiae, it could more effectively maintain the antioxidant property and storage capacity of curcumin under high temperature conditions. Simulated digestion was conducted to study in vitro release of curcumin encapsulated in APs, and showed a maximum bioaccessibility of 65.6 ± 3.8 %. In view of low-cost culture method, simple encapsulation process and high encapsulation capacity, G. candidum arthrospores as new natural encapsulation carriers have potential superiority in the practical application in food industry.
我们首次报道姜黄素成功包封于一种新型天然预制载体中，该载体源自益生菌白地霉LG-8的节孢子细胞壁颗粒（APs），主要由β-1,4-葡聚糖组成。采用真空注入法高效包封姜黄素。结果表明，APs的包封率和产率分别为36.5±0.9%和730.6±26.5μg/g（湿基）。与其他益生菌载体如酿酒酵母相比，它能在高温条件下更有效地保持姜黄素的抗氧化性能和储存能力。进行模拟消化以研究包封于APs中的姜黄素的体外释放，结果显示最大生物可及性为65.6±3.8%。鉴于低成本的培养方法、简单的包封工艺和高包封能力，白地霉菌节孢子作为新型天然包封载体在食品工业的实际应用中具有潜在优势。
