Department of Dermatology, The University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Department of Pathology, The University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
J Cutan Pathol. 2023 Mar;50(3):243-246. doi: 10.1111/cup.14350. Epub 2022 Nov 22.
Syringocystadenoma papilliferum (SCAP), tubular apocrine adenoma (TAA), and eccrine nevus are rare benign sweat gland tumors with varied clinical presentations but generally distinctive histomorphologic profiles. TAA and SCAP have been associated with other cutaneous hamartomas, most commonly with nevus sebaceus. Additionally, TAA and SCAP have uncommonly co-occurred in the same lesion. In contrast to nevus sebaceus, eccrine nevus is considerably less common and is rarely associated with other benign adnexal lesions. Here we present an unusual case of a complex sweat gland hamartoma containing features of syringocystadenoma papilliferum, tubular apocrine adenoma, and eccrine nevus in a 7-year-old female.
汗管囊腺瘤(SCAP)、管状大汗腺腺瘤(TAA)和小汗腺神经瘤是罕见的良性汗腺肿瘤,临床表现多样,但通常具有独特的组织形态学特征。TAA 和 SCAP 与其他皮肤错构瘤有关,最常见的是皮脂痣。此外,TAA 和 SCAP 也很少同时出现在同一病变中。与皮脂痣不同,小汗腺神经瘤则更为罕见,很少与其他良性附属器病变相关。本文报道了一例罕见的复杂汗腺错构瘤,该错构瘤在一名 7 岁女性中包含了汗管囊腺瘤、管状大汗腺腺瘤和小汗腺神经瘤的特征。