Crittenden Sunita C, Sonnier George B
Division of Dermatology, University of Louisville, Louisville, Kentucky.
Pediatr Dermatol. 2014 Mar-Apr;31(2):208-11. doi: 10.1111/pde.12269. Epub 2013 Dec 13.
Meningothelial hamartoma is a rare lesion of ectopic meningothelial elements that usually presents on the scalp at birth or in early childhood. The characteristic spindle cells infiltrate through collagen and stain positively for epithelial membrane antigen and vimentin but are negative for CD31 and CD34. This distinguishes meningothelial hamartoma from vascular tumors. Nevus sebaceus is a fairly common lesion that has been associated with several different benign tumors, including trichoblastoma and syringocystadenoma papilliferum. We describe the case of a 17-month-old girl who presented with a meningothelial hamartoma in association with a nevus sebaceus. To the best of our knowledge, this is the second case reported.
脑膜上皮错构瘤是一种罕见的异位脑膜上皮成分病变,通常在出生时或幼儿期出现在头皮上。其特征性的梭形细胞浸润穿过胶原,上皮膜抗原和波形蛋白染色呈阳性,但CD31和CD34染色呈阴性。这将脑膜上皮错构瘤与血管肿瘤区分开来。皮脂腺痣是一种相当常见的病变,与几种不同的良性肿瘤相关,包括毛母细胞瘤和乳头状汗腺囊腺瘤。我们描述了一名17个月大女孩的病例,她患有与皮脂腺痣相关的脑膜上皮错构瘤。据我们所知,这是第二例报告的病例。