Dosu Ayodeji, Gupta Mehak, Walsh Olivia, Makan Jayesh
Internal Medicine, The Shrewsbury and Telford Hospital National Health Service (NHS) Trust, Telford, GBR.
Cardiology, The Shrewsbury and Telford Hospital National Health Service (NHS) Trust, Telford, GBR.
Cureus. 2022 Sep 29;14(9):e29759. doi: 10.7759/cureus.29759. eCollection 2022 Sep.
Thyrotoxic hypokalaemic periodic paralysis (THPP) is a rare complication of hyperthyroidism that is potentially life-threatening if not treated promptly. It is more common in Asian and Polynesian populations and very few cases have been reported to date in people of White ethnicity. We present a case report of a young male patient of White ethnicity, who was initially brought in as a stroke alert with tetraparesis which was ruled out on initial assessment, but then had a syncopal episode and was noted to be initially bradycardic and subsequently tachycardic. Blood tests showed hypokalaemia and hypophosphataemia and he was treated as a hypokalaemic periodic paralysis patient. Intravenous potassium replacement was commenced. Symptoms and ECG changes resolved with correction of potassium levels. Thyroid function tests requested later were suggestive of hyperthyroidism and the diagnosis of thyrotoxic hypokalaemic periodic paralysis was made. This is an interesting case given its rarity, and this case report highlights the importance of early diagnosis and prompt treatment.
甲状腺毒症性低钾性周期性麻痹(THPP)是甲状腺功能亢进症的一种罕见并发症,若不及时治疗可能危及生命。它在亚洲和波利尼西亚人群中更为常见,迄今为止,白人种族中报告的病例很少。我们报告一例白人年轻男性患者,最初因四肢轻瘫作为卒中警报被送来,初步评估排除了卒中,但随后出现晕厥发作,最初被发现心动过缓,随后心动过速。血液检查显示低钾血症和低磷血症,他被作为低钾性周期性麻痹患者进行治疗。开始静脉补钾。随着血钾水平的纠正,症状和心电图变化得以缓解。后来进行的甲状腺功能检查提示甲状腺功能亢进,从而做出了甲状腺毒症性低钾性周期性麻痹的诊断。鉴于其罕见性,这是一个有趣的病例,本病例报告强调了早期诊断和及时治疗的重要性。